FLUORESCEIN ISOTHIOCYANATE-DEXTRAN Chemical Properties

storage temp. 

2-8°C

solubility 

H₂O: 50 mg/mL, slightly hazy, orange

form 

powder to crystaline

color 

Light yellow to Yellow to Orange

Safety Information

WGK Germany 

3

F 

3

HS Code 

2929100090

MSDS

• Language:English Provider:SigmaAldrich

FLUORESCEIN ISOTHIOCYANATE-DEXTRAN Usage And Synthesis

Chemical Properties

Dextran labeled with fluorescein isothiocyanate

Uses

Fluorescein isothiocyanate–dextran (FITC-Dextran 70) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-Dextran 70 may be used to study the capacity, selectivity and efficiency of encapsulation and release by drug delivery vehicles.

Uses

Fluorescein isothiocyanate–dextran (FITC-Dextran 150) is use as a fluorescent probe to study cell permeability. FITC-Dextran 150 is useful to study processes that affect the permeability of the blood brain barrier (BBB) and microvascular structures. FITC-Dextran 150 is used in fluorescence microlymphography.

Uses

water soluble cellulase substrate

General Description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran. Conflicting data on the branch lengths implies that the average branch length is less than three glucose units. However, other methods indicate branches of greater than 50 glucose units exist. Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. Lower MW dextrans will exhibit slightly less branching and have a more narrow range of MW distribution. Dextrans with MW greater than 10,000 behave as if they are highly branched. As the MW increases, dextran molecules attain greater symmetry. Dextrans with MW of 2,000 to 10,000, exhibit the properties of an expandable coil. At MW below 2,000, dextran is more rod-like. The MW of dextran is measured by one or more of the following methods: low angle laser light scattering, size exclusion chromatography, copper-complexation and anthrone reagent colorometric reducing-end sugar determination and viscosity.

FLUORESCEIN ISOTHIOCYANATE-DEXTRAN(60842-46-8)Related Product Information

• Fluorescein isothiocyanate
• Fluorescein isothiocyanate isomer I
• Guanidine thiocyanate
• 6-FITC
• RHODAMINE B ISOTHIOCYANATE
• ETHYL ISOTHIOCYANATOACETATE
• Methoxycarbonyl isothiocyanate
• Methyl isothiocyanate
• CYCLOPROPYL ISOTHIOCYANATE
• Butyl isothiocyanate
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
• COBALT(II) ACETYLACETONATE
• TERT-BUTYL ISOCYANIDE
• Ethyl isocyanoacetate
• Benzyl isocyanide
• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• Tris(2,4-pentanedionato)chroMiuM(III)