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APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE

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APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE Basic information

Product Name:
APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE
Synonyms:
  • 8-(α-L-Arabinopyranosyl)-6-(β-D-glucopyranosyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • Shaftoside
  • Apigenin 8-C-α-L-arabinoside 6-C-β-D-glucoside
  • 6-C-beta-D-Glucosyl-8-C-alpha-L-arabinosylapigenin
  • 4',5,7-Trihydroxy-6-(β-D-glucopyranosyl)-8-(α-L-arabinopyranosyl)flavone
  • Schaftoside, 98%, from Desmodium styracifolium (Osbeck) Merr.
  • 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]-4H-chromen-4-one (non-preferred name)
  • 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2ytetrahydH-chromen-4-one (non-preferred name)
CAS:
51938-32-0
MF:
C26H28O14
MW:
564.5
EINECS:
218-362-5
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • plant extract
  • Tri-substituted Flavones
Mol File:
51938-32-0.mol
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APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE Chemical Properties

Melting point:
228℃
Boiling point:
935.0±65.0 °C(Predicted)
Density 
1.766
storage temp. 
2-8°C
solubility 
DMSO : 250 mg/mL (442.88 mM; Need ultrasonic)
form 
Solid
pka
5.70±0.40(Predicted)
color 
Yellow
InChIKey
NIABBGMPPWXWOJ-JQSBCWDXSA-N
SMILES
OC1=C([C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C(O)=C2C(C=C(C3C=CC(O)=CC=3)OC2=C1[C@@H]1OC[C@H](O)[C@H](O)[C@H]1O)=O |&1:3,4,5,7,9,30,33,35,37,r|
LogP
0.040 (est)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
DJ2977250
HS Code 
29389090
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APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, derived from Desmodium styracifolium.

Uses

Schaftoside is an inhibitor of cholestorol gallstone formation. Prevents hepatic fatty degeneration in mice.

Definition

ChEBI: A C-glycosyl compound that is apigenin substituted by beta-D-glucopyranosyl and an alpha-L-arabinopyranosyl moieties at positions 6 and 8 via C-glycos dic linkages.

IC 50

TLR4

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