3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO: 10mg/mL

form 

Light brown solid.

color 

light brown

InChI

1S/C15H10ClN3O/c16-10-6-4-9(5-7-10)13-8-18-12-3-1-2-11(15(17)20)14(12)19-13/h1-8H,(H2,17,20)

InChIKey

FLYGLPYJEQPCFY-UHFFFAOYSA-N

SMILES

Clc1ccc(cc1)c2nc3c(nc2)cccc3C(=O)N

Safety Information

WGK Germany 

WGK 1

Storage Class

11 - Combustible Solids

3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE Usage And Synthesis

Uses

A potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC₅₀ = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.

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