ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Borate > N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Basic information
- Product Name:
- N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
- Synonyms:
-
- N-BOC-1,2,5,6-TETRAHYDROPYRIDINE-4-(PINACOLATO)BORONATE
- (N-TERT-BUTOXYCARBONYL)-1,2,3,6-TETRAHYDROPYRIDINE-4-BORONIC ACID PINACOL ESTER
- 4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- 3,6-DIHYDRO-2H-PYRIDINE-1-TERT-BUTOXYCARBONYL-4-BORONIC ACID, PINACOL ESTER
- 1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE
- 1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE 98+%
- N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
- tert-butyl 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine
- CAS:
- 286961-14-6
- MF:
- C16H28BNO4
- MW:
- 309.21
- EINECS:
- 689-148-0
- Product Categories:
-
- API intermediates
- Organoborons
- Pyridine
- Mol File:
- 286961-14-6.mol
More
Less
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Chemical Properties
- Melting point:
- 114.0 to 118.0 °C
- Boiling point:
- 348.0±52.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Dichloromethane (Sparingly), DMSO (Slightly)
- pka
- -1.21±0.40(Predicted)
- form
- Solid
- color
- white to off-white
- Water Solubility
- Soluble in most organic solvents. Insoluble in water.
- InChI
- InChI=1S/C16H28BNO4/c1-14(2,3)20-13(19)18-10-8-12(9-11-18)17-21-15(4,5)16(6,7)22-17/h8H,9-11H2,1-7H3
- InChIKey
- VVDCRJGWILREQH-UHFFFAOYSA-N
- SMILES
- C1N(C(OC(C)(C)C)=O)CC=C(B2OC(C)(C)C(C)(C)O2)C1
More
Less
More
Less
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Usage And Synthesis
Chemical Properties
off-white powder
Uses
Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.
Uses
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester is an intermediate for organic synthesis and pharmaceutical research and development, and can be used for suzuki reaction.
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol esterSupplier
AllyChem Co., Ltd. Gold
- Tel
- 0411-62313318 13942603642
- info@allychem.com
Shanghai Arbor Chemical Co., Ltd. Gold
- Tel
- 021-60451682 15021268886
- sales@arborchemical.com
Tianshui YiYao Chemical Co., Ltd. Gold
- Tel
- 0938-0938-8493022 15379872136
- xiaoshi079@163.com
ShenZhen Trendseen Biological Technology Co.,Ltd. Gold
- Tel
- 13417589054 13417589054
- trendseenbio@gmail.com
Anqing Xinheyuan Pharmaceutical Technology Co., Ltd Gold
- Tel
- 18915922978 15270619650
- xiang.ru@synovent.cn
More
Less
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester(286961-14-6)Related Product Information
- Pinacol
- Pyridine hydrobromide
- Propyleneglycol alginate
- Tris(trimethylsilyl)phosphate
- Methyl acrylate
- Pyridine
- Diethyl phthalate
- Pyridine hydrofluoride
- 1,1'-Carbonyldiimidazole
- Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- Dimethyl succinate
- 2,2,4-Trimethyl-1,3-pentanediol monoisobutyrate
- Dihydromyrcenol
- tert-butyl 4-(4-amino-2-methoxyphenyl)piperazine-1-carboxylate
- tert-butyl 4-(4-hydroxybutyl)piperazine-1-carboxylate
- N-BOC-1,2,3,6-TETRAHYDROPYRIDINE
- N-BOC-3-Aminopiperidine
- N-Boc-4-iodopiperidine