D-Mannosamine hydrochloride Chemical Properties

Melting point:

168 °C (dec.)(lit.)

storage temp. 

2-8°C

solubility 

H₂O: 0.1 g/mL, clear, colorless

form 

Powder

color 

White to Off-white

Water Solubility 

Soluble in water and methanol.

Sensitive 

Hygroscopic

BRN 

3914860

InChIKey

QKPLRMLTKYXDST-OHXGPSCHSA-N

CAS DataBase Reference

5505-63-5(CAS DataBase Reference)

EPA Substance Registry System

D-Mannose, 2-amino-2-deoxy-, hydrochloride (5505-63-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

WGK Germany 

3

F 

3-10

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29329985

MSDS

• Language:English Provider:SigmaAldrich

D-Mannosamine hydrochloride Usage And Synthesis

Chemical Properties

D-Mannosamine hydrochloride is White Crystalline Solid

Uses

D-Mannosamine hydrochloride is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery via M cells of Peyer's patches.

Uses

D-Mannosamine hydrochloride can be used for the synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. It has been used in a study to investigate the synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis.

Uses

D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer's patches.

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