2,3-Dihydroxybenzoic acid Chemical Properties

Melting point:

204-206 °C (lit.)

Boiling point:

95-96/0.5mm

Density 

1,542 g/cm³

refractive index 

1.6400 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

methanol: soluble50mg/mL, clear to faintly hazy, orange

pka

pK1:2.98;pK2:10.14 (30°C)

form 

Crystalline Powder

color 

Beige to brown or pinkish-gray

Water Solubility 

Soluble in water, methanol and dimethyl sulfoxide.

BRN 

2209117

InChIKey

GLDQAMYCGOIJDV-UHFFFAOYSA-N

LogP

1.200

CAS DataBase Reference

303-38-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 2,3-dihydroxy-(303-38-8)

EPA Substance Registry System

2,3-Dihydroxybenzoic acid (303-38-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

2

RTECS 

DG8576490

Hazard Note 

Irritant

HS Code 

29182900

MSDS

• Language:English Provider:2,3-Dihydroxybenzoic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,3-Dihydroxybenzoic acid Usage And Synthesis

Chemical Properties

Pale Brownish to Red Brownish Crystalline Powder. 2,3-Dihydroxybenzoic Acid [303-38-8], C7H6O4, Mr 154.1, mp 206℃, undergoes decomposition to catechol and carbon dioxide. The acid crystallizes from water as a dihydrate. Among other uses, it serves as an iron-complexing agent in drugs.

Uses

2,3-Dihydroxybenzoic Acid is a selected phenol as MMP (Matrix Metalloproteinase) inhibitor.

Uses

2,3-Dihydroxybenzoic acid was used to study the complexes of manganese with aliphatic and aromatic polyhydroxy ligands in basic media by electrochemical, spectrophotometric and magnetic methods. It was used in isolation of new siderophore named vulnibactin from low iron cultures of Vibrio vulnificus, a human pathogen. It was used as cocrystal former to study the influence of position isomerism on the co-crystals formation and physicochemical properties of piracetam.

Definition

ChEBI: A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.

Biochem/physiol Actions

2,3-Dihydroxybenzoic acid was found to be orally effective iron-chelating drug in hypertransfused rat model. It is monocatechol siderophore produced by Brucella abortus.

2,3-Dihydroxybenzoic acid(303-38-8)Related Product Information

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