Basic information Safety Supplier Related

N-PALMITOYL-D-SPHINGOMYELIN

Basic information Safety Supplier Related

N-PALMITOYL-D-SPHINGOMYELIN Basic information

Product Name:
N-PALMITOYL-D-SPHINGOMYELIN
Synonyms:
  • P-SPM
  • n-palmitoyl-d-sphingomyelin semisynthetic from bovine brain sphingomyelin
  • N-palMitoyl-D-erythro-sphingosylphosphorylcholine
  • (2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-3-hydroxy-1-phosphocholine
  • 16:0 SM (d18:1/16:0)
  • C16 Sphingomyelin
  • N-(Hexadecanoyl)-sphing-4-enine-1-phosphocholine
  • N-PALMITOYL-D-ERYTHRO-SPHINGOSYLPHOSPHORYLCHOLINE;16:0 SM (D18:1/16:0)
CAS:
6254-89-3
MF:
C39H79N2O6P
MW:
703.028121
Mol File:
6254-89-3.mol
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N-PALMITOYL-D-SPHINGOMYELIN Chemical Properties

storage temp. 
−20°C
solubility 
Ethanol: 10 mg/ml
form 
powder or crystals
color 
White to off-white
BRN 
4833682
InChIKey
RWKUXQNLWDTSLO-UWSOPVLFNA-N
SMILES
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N([H])C(=O)CCCCCCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C |&1:15,17,r|
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Safety Information

WGK Germany 
3
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N-PALMITOYL-D-SPHINGOMYELIN Usage And Synthesis

Uses

N-palmitoyl-D-erythro-sphingosylphosphorylcholine (16:0 SM (d18:1/16:0)) has been used as a standard for the quantitation of sphingolipid metabolites. It has also been used for the quantification of lipids in green fluorescence protein (GFP) and fatty acid transport protein 4 (FATP4) cells using electrospray ionization tandem mass spectrometry (ESI-MS/MS). It may be used in liposomes to measure ostreolysin A (OlyA) binding to determine the effects of phosphatidylcholines (PCs) on sphingomyelin (SM)/cholesterol interactions.

Definition

ChEBI: A sphingomyelin 34:1 in which the N-acyl group and sphingoid base are specified as hexadecanoyl and sphingosine respectively.

in vivo

N-Palmitoyl-D-Sphingomyelin (100 ?μM, 3 days) combined with a respiratory chain inhibitor rescues cell death induction in HCT116 spheroids[2].

N-PALMITOYL-D-SPHINGOMYELINSupplier

Shanghai Jindi Pharmaceutical Technology Co., Ltd Gold
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13564401937
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wangtao@jindipharma.com.cn
Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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cwb1@biopurify.cn
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 13167063860
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anhua.mao@aladdin-e.com
Yichang Zhongyitai Trading Co., Ltd.
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0717-6449896 13886658719
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root@zhongyitai.com
Shanghai AECOM Biotechnology Co. , Ltd.
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021-021-20956531 18116226605
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sui@neosunpharm.com