ChemicalBook > Product Catalog > Organic Chemistry > Hydrocarbons and derivatives > Hydrocarbon nitrification > 2-Chloro-4-nitrobenzoic acid
2-Chloro-4-nitrobenzoic acid
2-Chloro-4-nitrobenzoic acid Basic information
- Product Name:
- 2-Chloro-4-nitrobenzoic acid
- Synonyms:
-
- 2-CHLORO-4-NITROBENZOIC ACID FOR SYNTHES
- 2-chloro-4-nitrobenzoic
- 2-chloro-4-nitro-benzoicaci
- Benzoicacid,2-chloro-4-nitro-
- kyselina2-chloro-4-nitrobenzoova
- NSC 150
- TIMTEC-BB SBB000403
- RARECHEM AL BO 0521
- CAS:
- 99-60-5
- MF:
- C7H4ClNO4
- MW:
- 201.56
- EINECS:
- 202-771-0
- Product Categories:
-
- Organic acids
- C7
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
- Carbonyl Compounds
- Carboxylic Acids
- Pyridines
- 99-60-5
- Mol File:
- 99-60-5.mol
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2-Chloro-4-nitrobenzoic acid Chemical Properties
- Melting point:
- 136-140 °C(lit.)
- Boiling point:
- 160.5°C (rough estimate)
- Density
- 1.5719 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Crystalline Powder
- pka
- pK1: 1.96 (25°C)
- color
- Light yellow to light green
- Water Solubility
- 1 g/L (20 ºC)
- BRN
- 1912836
- InChI
- InChI=1S/C7H4ClNO4/c8-6-3-4(9(12)13)1-2-5(6)7(10)11/h1-3H,(H,10,11)
- InChIKey
- QAYNSPOKTRVZRC-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=C([N+]([O-])=O)C=C1Cl
- CAS DataBase Reference
- 99-60-5(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 2-chloro-4-nitro- (99-60-5)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-41-37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- DG5425000
- TSCA
- Yes
- HS Code
- 29163900
MSDS
- Language:English Provider:2-Chloro-4-nitrobenzoic acid
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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2-Chloro-4-nitrobenzoic acid Usage And Synthesis
Chemical Properties
light yellow to light green crystalline powder
Uses
The active pharmaceutical ingredient 2-chloro-4-nitrobenzoic acid (2c4n) is a potentially novel therapy for immunodeficiency diseases as an anti-viral and anti-cancer agent and is a dimorph in the solid state. 2c4n is a historically significant compound from a polymorphic point of view, as it was one of the samples used by Ebert and Gottlieb to show that polymorphs can be identified or differentiated through their IR spectra back in 1952[1].
References
[1] Andreas Lemmerer, Joel Bernstein, Catharine Esterhuysen. “Synthesis, characterization, and molecular modeling of a pharmaceutical co-crystal: (2-chloro-4-nitrobenzoic acid):(nicotinamide)?.” Journal of pharmaceutical sciences 99 9 (2010): 4054–4071.
2-Chloro-4-nitrobenzoic acid Preparation Products And Raw materials
Preparation Products
Raw materials
2-Chloro-4-nitrobenzoic acidSupplier
LEWOO PHARMATECH (SHANGHAI) CO.,LTD Gold
- Tel
- 15800805830
- miao@lewoopharma.com.cn
Jinan Dexinjia Bio&Tech Co., Ltd Gold
- Tel
- 0531-82375886 13001715031
- 3517280075@qq.com
Shanghai Witofly Chemical Co. ,Ltd. Gold
- Tel
- 021-5063062 15300832537
- sales@witofly.com
Shanghai Qiao Chemical Science Co., Ltd Gold
- Tel
- 021-58892003
- info@qiaochem.com
Nanjing Searchem Co., Ltd. Gold
- Tel
- 15105140861
- sikai@searchem.cn
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