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L(+)-Ornithine hydrochloride

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L(+)-Ornithine hydrochloride Basic information

Product Name:
L(+)-Ornithine hydrochloride
Synonyms:
  • L-ORNITHINE HYDROCHLORIDE SALT
  • L-(+)-ORNITHINE MONOHYDROCHLORIDE
  • L-ORNITHINE MONOHYDROCHLORIDE
  • L-ORNITHINE-OH HCL
  • L-ORNITHINE-OH HYDROCHLORIDE
  • L-ORN HCL
  • L-ORNITHINE HCL
  • L(+)-ORNITHINE HYDROCHLORIDE
CAS:
3184-13-2
MF:
C5H13ClN2O2
MW:
168.62
EINECS:
221-678-6
Product Categories:
  • amino
  • Amino hydrochloride
  • alpha-Amino Acids
  • Amino Acids
  • Biochemistry
  • non-Proteinorganic Amino Acids
  • Amino Acid Derivatives
  • Ornithine [Org]
  • Amino Acids and Derivatives
  • L-Amino Acids
  • Amino Acids & Derivatives
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • bc0001
Mol File:
3184-13-2.mol
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L(+)-Ornithine hydrochloride Chemical Properties

Melting point:
245 °C (dec.)(lit.)
alpha 
24 º (c=4, 6N HCl)
Density 
1.57
FEMA 
4190 | L-ORNITHINE MONOCHLOROHYDRATE/ORNITHINE
refractive index 
24 ° (C=4, 6mol/L HCl)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: 100 mg/mL
form 
Powder
color 
White
PH
5.0-6.0 (25℃, 1M in H2O)
Odor
at 100.00 %. mild green bark
Odor Type
green
optical activity
[α]20/D +23.0±0.5°, c = 5% in 5 M HCl
Water Solubility 
Soluble in water (543 mg/ml at 20°C), and alcohol.
λmax
λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.06
JECFA Number
2120
Merck 
14,6874
BRN 
3625847
Stability:
Stable.
InChIKey
GGTYBZJRPHEQDG-WCCKRBBISA-N
LogP
-4.22
CAS DataBase Reference
3184-13-2(CAS DataBase Reference)
EPA Substance Registry System
L-Ornithine, monohydrochloride (3184-13-2)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-36
Safety Statements 
24/25-37/39-26
WGK Germany 
3
RTECS 
RM2985000
3-10
TSCA 
Yes
HS Code 
29224995
Toxicity
LD50 orl-rat: 10 g/kg JPMSAE 62,49,73

MSDS

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L(+)-Ornithine hydrochloride Usage And Synthesis

Chemical Properties

White powder; mild green bark aroma.

Chemical Properties

L(+)-Ornithine hydrochloride is white crystalline powder

Uses

L(+)-Ornithine hydrochloride is a nonprotein amino acid used in the biosynthesis of L-arginine, L-proline and polyamines.

Uses

L(+)-Ornithine hydrochloride is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis. L(+)-Ornithine hydrochloride is found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta.

Uses

Non-essential amino acid for human development but is required intermediate in arginine biosynthesis. Found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta.

Aroma threshold values

Low strength odor, green type.

Taste threshold values

Very mild sweet taste at 500.00 ppm in water.

General Description

L-Ornithine is the functional metabolite of L-arginine.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.

Safety Profile

Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Purification Methods

Likely impurities are citrulline, arginine and D-ornithine. Crystallise the monohydrochloride from water by adding 4volumes of EtOH and dry it in a vacuum desiccator over fused CaCl2. [Rivard Biochemical Preparations 3 98 1955.] The dihydrochloride [6211-16-1] has m 202-203o and [ ] D +18.4o (c 2.3, 6N HCl) after recrystallisation from MeOH/Et2O [Zaoral & Rudinger Collect Czech Chem Commun 24 2009 1959]. [Beilstein 4 IV 2644.]

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