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(2-PHENOXY)METHYLSULFONYLANILINE

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(2-PHENOXY)METHYLSULFONYLANILINE Basic information

Product Name:
(2-PHENOXY)METHYLSULFONYLANILINE
Synonyms:
  • 2-PHENOXYMETHANESULFOANILIDE
  • 2-PHENOXYMETHANESULFONANILIDE
  • Nimesulide EP Impurity B,(N-（2-phenoxyphenyl)methanesulfonamide)
  • (2-PHENOXY)METHYLSULFONYLANILINE
  • N-(2-phenoxyphenyl)methanesulphonamide
  • 2-Phenoxymethanesulfonailide
  • Einecs 257-399-1
  • Nimesulide impurity-B(EP/BP)
CAS:
51765-51-6
MF:
C13H13NO3S
MW:
263.31
EINECS:
257-399-1
Mol File:
51765-51-6.mol
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(2-PHENOXY)METHYLSULFONYLANILINE Chemical Properties

Melting point:
126℃
Boiling point:
378.9±44.0 °C(Predicted)
Density 
1.313
vapor pressure 
0Pa at 25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), DMSO
form 
Solid
pka
8.43±0.10(Predicted)
color 
White to Off-White
Water Solubility 
176.1mg/L at 25℃
LogP
2.4 at 25℃
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(2-PHENOXY)METHYLSULFONYLANILINE Usage And Synthesis

Uses

2''-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production.

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TAIYUAN RHF CO.,LTD.
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(2-PHENOXY)METHYLSULFONYLANILINE(51765-51-6)Related Product Information