BZ-GLU-OH Chemical Properties

Melting point:

140 °C

Boiling point:

562.0±40.0 °C(Predicted)

Density 

1.354±0.06 g/cm3(Predicted)

refractive index 

18.5 ° (C=10, 1mol/L NaOH)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

Water Solubility 

very faint turbidity in hot Water

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

pka

3.61±0.10(Predicted)

form 

Solid

color 

White to Almost white

CAS DataBase Reference

6094-36-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

Hazard Note 

Irritant

HS Code 

2924.29.7790

BZ-GLU-OH Usage And Synthesis

Chemical Properties

Crystalline

Synthesis

In a reaction vessel fitted with a stirrer and a dropping funnel, 3.5 L of potassium carbonate solution with a mass fraction of 70% was added, and the temperature of the solution was lowered to 7 ??C, . L-glutamic acid (2) 4.1 mol was added slowly, the stirring speed was controlled at 190 rpm, and two dropping funnels were used to add 4.15 mol of chloromethylstyrene solution and 80% methylenebenzene solution. Liquid and mass fraction of 80% sodium bisulfite solution 1800ml, control the temperature of the solution is 19 ??, control the reaction pH is maintained at 10, all added After continue to maintain the stirring speed of 60min, add the mass fraction of 30% oxalic acid solution to maintain the pH at 6, reduce the temperature of the solution to 3 ??, stand for 30h, . Filter out the solid, mix the solid with 1100 ml of 20% potassium chloride solution, maintain the temperature of the solution at 6 ??, continue to stir until the solid precipitated, filtration, toluene solution was added to maintain the pH at 6 ??, and the solution was allowed to stand for 30h. precipitated, extracted, toluene solvent washing, anhydrous potassium carbonate dehydration, obtained N-benzyl-L-glutamic acid 782.12g, yield 76%.

BZ-GLU-OH(6094-36-6)Related Product Information

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• P-NITROBENZOYL-L-GLUTAMIC ACID
• BZ-GLU-OH
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• Z-GLU-OME
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• N-(4-NITROBENZOYL)-L-GLUTAMIC ACID DIETHYL ESTER
• FOLINIC ACID CALCIUM SALT PENTAHYDRATE
• DIHYDROFOLIC ACID DIHYDRATE
• 4-AMINOFOLIC ACID HYDRATE