ChemicalBook > Product Catalog > Pharmaceutical intermediates > Bulk Drug Intermediates > 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Basic information
- Product Name:
- 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
- Synonyms:
-
- 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
- N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
- 4-(3-chloro-4-fiuoro-phen...
- 4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline
- N-(3-chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetaMide
- (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine
- N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine
- Afatinib intermediate A
- CAS:
- 162012-67-1
- MF:
- C14H7ClF2N4O2
- MW:
- 336.68
- EINECS:
- 000-000-0
- Product Categories:
-
- API intermediates
- 162012-67-1
- Mol File:
- 162012-67-1.mol
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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Chemical Properties
- Melting point:
- 242-244℃
- Boiling point:
- 489℃
- Density
- 1.616
- Flash point:
- 249℃
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 5.07±0.70(Predicted)
- color
- Yellow to Dark Yellow
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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Usage And Synthesis
Uses
4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-Supplier
Jinan XuanDe Chemical Co., Ltd. Gold
- Tel
- 0531-88803958; 18866891188
- zhaojiangxia@shiningpharm.com
Anhui Dexinjia Biopharm Co., Ltd Gold
- Tel
- 0531-82375878 15269101859
- 2710825968@qq.com
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
- Tel
- 022-60182192,1339732154 18722583064
- marketing@pharmacn.com
BeiJing Hwrk Chemicals Limted
- Tel
- 0757-86329057 18934348241
- sales4.gd@hwrkchemical.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-(162012-67-1)Related Product Information
- N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
- Aprepitant
- methyl(E)-4-(methylamino)but-2-enoate
- (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride
- (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- TRANS-4-AMINOCROTONIC ACID
- 7-Fluoro-4-quinazolone
- Afatinib impurity 45
- Benzyl dihydrogen phosphate
- (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine
- trans-4-Dimethylaminocrotonic acid hydrochloride
- (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine
- Afatinib
- Afatinib dimaleate
- (S)-(+)-3-Hydroxytetrahydrofuran
- Afatinib (BIBW 2992)
- 7-Fluoro-6-nitro-4-hydroxyquinazoline
- 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-