2-Iodobenzyl bromide Chemical Properties

Melting point:

54-60 °C(lit.)

Boiling point:

125 °C / 4mmHg

Density 

2.105±0.06 g/cm3(Predicted)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

soluble in Methanol

form 

Crystalline Powder

color 

White to cream

Sensitive 

Light Sensitive

BRN 

2079736

CAS DataBase Reference

40400-13-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

C,N,T

Risk Statements 

22-34-43-51/53-63-42/43-36/37/38

Safety Statements 

26-36/37/39-61-45-23

RIDADR 

UN 3261 8/PG 2

WGK Germany 

2

HazardClass 

8

PackingGroup 

Ⅱ

HS Code 

29039990

MSDS

• Language:English Provider:2-Iodobenzyl bromide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Iodobenzyl bromide Usage And Synthesis

Application

2-Iodobenzylmethyl bromide is a halocarbon compound mainly used in laboratory research and development processes and chemical production processes.

Chemical Properties

White solid

Synthesis

General procedure for the synthesis of 2-iodobenzyl bromide from 2-iodobenzyl alcohol: 48% hydrobromic acid (10 mL) and 98% sulfuric acid (2 mL) were added to 2-iodobenzyl alcohol (0.94 g, 4.0 mmol). The resulting suspension was placed in an oil bath and heated and stirred at 150 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with dichloromethane (2 x 10 mL). The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (silica gel, 0-20% dichloromethane/hexane gradient elution) to afford the target compound 2-iodobenzyl bromide (1.0 g, 84% yield).

References

[1] Tetrahedron, 2005, vol. 61, # 13, p. 3311 - 3324
[2] Journal of Organic Chemistry, 2012, vol. 77, # 13, p. 5705 - 5713
[3] Helvetica Chimica Acta, 1995, vol. 78, p. 765 - 771
[4] Tetrahedron, 1993, vol. 49, # 20, p. 4439 - 4446
[5] Tetrahedron, 2002, vol. 58, # 44, p. 9007 - 9018

2-Iodobenzyl bromide(40400-13-3)Related Product Information

• 1,2-Diiodobenzene
• Bromotrimethylsilane
• Rocuronium bromide
• 2-Iodobenzoic acid
• Ethidium bromide
• Allyl bromide
• 2-(Trifluoromethyl)benzyl chloride
• 2-Bromophenol
• 1,4-Diiodobenzene
• 2-(Chloromethyl)benzonitrile
• (Diacetoxyiodo)benzene
• alpha-Chloro-o-fluorotoluene
• 2-Chlorobenzyl chloride
• Benzyl bromide
• Sodium bromate
• 4-Nitrobenzyl bromide
• Methyl bromide
• 3-IODOBENZYL BROMIDE,M-IODOBENZYL BROMIDE,m-Iodobenzyl Bromide 3-Iodobenzyl Bromide,3-Iodobenzyl bromide, 98+%,3-Iodobenzyl bromide 99%