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PROSTAGLANDIN J2

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PROSTAGLANDIN J2 Basic information

Product Name:
PROSTAGLANDIN J2
Synonyms:
  • 11-OXO-15S-HYDROXY-PROSTA-5Z,9,13E-TRIEN-1-OIC ACID
  • (5Z,13E,15S)-15-HYDROXY-11-OXOPROSTA-5,9,13-TRIEN-1-OIC ACID
  • PROSTAGLANDIN J2
  • PGJ2
  • 9-deoxy-delta-9-prostaglandind2
  • PROSTAGLANDIN J2, 5MG/ML IN METHYL ACETA
  • (Z)-7-[(1S,5R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxo-1-cyclopent-2-enyl]hept-5-enoic acid
  • (5Z,13E,15S)-15-Hydroxy-11-oxoprosta-5,9,13-triene-1-oic acid
CAS:
60203-57-8
MF:
C20H30O4
MW:
334.45
EINECS:
201-185-2
Mol File:
60203-57-8.mol
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PROSTAGLANDIN J2 Chemical Properties

Boiling point:
521.7±50.0 °C(Predicted)
Density 
1.103±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-.DEL
pka
4.75±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Safety Information

Hazard Codes 
Xn,Xi,F
Risk Statements 
20/21/22-36/37/38-67-66-36-11
Safety Statements 
26-36-33-29-16
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PROSTAGLANDIN J2 Usage And Synthesis

Description

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM. PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines. However, this activity has been attributed to further metabolites of PGJ2 and not the parent compound itself.

Uses

PGJ2 (Prostaglandin J2) is a Prostaglandin D2 metabolite that has shown potent anti-neoplastic and antiviral activity.

Definition

ChEBI: A member of the class of prostaglandins J that consists of prosta-5,9,13-trien-1-oic acid substituted by an oxo group at position 11 and a hydroxy group at position 15 (the 5Z,13E,15S stereoisomer).

PROSTAGLANDIN J2Supplier

Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
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market@aladdin-e.com
Aikon International Limited
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025-58851090 13611564524
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lwan@aikonchem.com
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
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0571-85361029
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synstar518@163.com
BOC Sciences
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info@bocsci.com
Career Henan Chemica Co
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+86-0371-86658258 +8613203830695
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laboratory@coreychem.com