ARTEMISETIN(P) Chemical Properties

Melting point:

261～264℃

Boiling point:

588.8±50.0 °C(Predicted)

Density 

1.37±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: Soluble
Methanol: Soluble

form 

powder

pka

6.12±0.40(Predicted)

color 

Yellow

Water Solubility 

Slightly soluble in water

InChI

InChI=1S/C20H20O8/c1-23-11-7-6-10(8-12(11)24-2)18-20(27-5)17(22)15-13(28-18)9-14(25-3)19(26-4)16(15)21/h6-9,21H,1-5H3

InChIKey

RIGYMJVFEJNCKD-UHFFFAOYSA-N

SMILES

C1(C2=CC=C(OC)C(OC)=C2)OC2=CC(OC)=C(OC)C(O)=C2C(=O)C=1OC

LogP

2.550 (est)

Safety Information

HS Code 

29329990

ARTEMISETIN(P) Usage And Synthesis

Chemical Properties

Orange needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the aerial parts of wormwood, bitter wormwood, and stinky elixir.

Uses

Artemitin has an anti-tumor, anti-inflammatory, antibacterial, blood pressure lowering effects.

Definition

ChEBI: Artemetin is a member of flavonoids and an ether.

Biological Activity

Artemitin is a natural flavonoid found in Heliconia chinensis with antioxidant, anti-inflammatory, and antiviral effects.

References

[1] ALTON J. DUGAS JR. Evaluation of the Total Peroxyl Radical-Scavenging Capacity of Flavonoids: Structure−Activity Relationships[J]. Journal of Natural Products , 2000, 63 3: 327-331. DOI: 10.1021/np990352n
[2] M IQBAL CHOUDHARY. Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus.[J]. Phytotherapy Research, 2009, 23 9: 1336-1339. DOI: 10.1002/ptr.2639
[3] K C LIU. Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures.[J]. Plant Cell Reports, 1992, 11 12: 637-640. DOI: 10.1007/bf00236389
[4] W.G KO. Polymethoxyflavonoids from Vitex rotundifolia inhibit proliferation by inducing apoptosis in human myeloid leukemia cells[J]. Food and Chemical Toxicology, 2000, 38 10: Pages 861-865. DOI: 10.1016/s0278-6915(00)00079-x
[5] PRISCILA DE SOUZA . Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats[J]. Phytomedicine, 2011, 18 10: Pages 819-825. DOI: 10.1016/j.phymed.2011.02.005

ARTEMISETIN(P)(479-90-3)Related Product Information

• ABSINTHIN
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• Aluminum acetylacetonate
• N-BUTYLISOCYANIDE
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
• COBALT(II) ACETYLACETONATE
• Ethyl isocyanoacetate
• TERT-BUTYL ISOCYANIDE
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
• Benzyl isocyanide
• Tris(2,4-pentanedionato)chroMiuM(III)
• Ferric acetylacetonate
• PHENYLSELENOL
• SALCOMINE
• METHYL ISOCYANOACETATE
• 2,4-PENTANEDIONE, SILVER DERIVATIVE
• Tosylmethyl isocyanide
• 5-HYDROXYFLAVONE