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3-Hydroxy-4-methoxyphenylacetic acid

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3-Hydroxy-4-methoxyphenylacetic acid Basic information

Product Name:
3-Hydroxy-4-methoxyphenylacetic acid
Synonyms:
  • HOMOISOVANILLIC ACID
  • 3-HYDROXY-4-METHOXYPHENYLACETIC ACID
  • 2-(3-hydroxy-4-methoxy-phenyl)acetic acid
  • Isohomovanillic acid
  • methyl 2-(3-hydroxy-4-methoxyphenyl)acetate
  • 3-Hydroxy-4-methoxyphenylacetic acid ,98%
  • 3-Hydroxy-4-Methoxybenzeneacetic Acid
  • 4-Methoxy-3-hydroxyphenylacetic Acid
CAS:
1131-94-8
MF:
C9H10O4
MW:
182.17
EINECS:
670-463-7
Product Categories:
  • Multisubstituted Benzene
  • Acids and Derivatives
  • Alcohols and Derivatives
  • Aromatic Phenylacetic Acids and Derivatives
  • Phenylacetic acid
  • API intermediates
  • Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
1131-94-8.mol
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3-Hydroxy-4-methoxyphenylacetic acid Chemical Properties

Melting point:
127-132 °C
Boiling point:
371.3±27.0 °C(Predicted)
Density 
1.307±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.36±0.10(Predicted)
color 
Pale Beige
CAS DataBase Reference
1131-94-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29189900
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3-Hydroxy-4-methoxyphenylacetic acid Usage And Synthesis

Chemical Properties

Pale Beige Solid

Uses

3-Hydroxy-4-methoxyphenylacetic acid is a 4-O-methylated metabolite of catechol amines in man. 3-Hydroxy-4-methoxyphenylacetic acid is also a metabolite of 3,4-dihydroxyphenylalanine (DOPA) analogues as well as a metabolite of Hydroxytyrosol (H977000).

Definition

ChEBI: A monocarboxylic acid that is the 4-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 2061, 1984 DOI: 10.1021/jo00185a061

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