Basic information Safety Supplier Related

Polymyxin B

Basic information Safety Supplier Related

Polymyxin B Basic information

Product Name:
Polymyxin B
Synonyms:
  • polymyxin B 2.5sulfate entahydrate
  • Polymyxin B (base and/or unspecified salts)
  • Polymyxin E see Colistin
  • Glucosamine Hydrochloride Impurity 32
CAS:
1404-26-8
MF:
C55H96N16O13
MW:
0
EINECS:
215-768-4
Mol File:
Mol File
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Polymyxin B Chemical Properties

alpha 
5461 -106.3° (1N HCl)
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Polymyxin B Usage And Synthesis

Description

Polymyxin B was isolated by Wellcome Research Laboratories, in 1949, from the mixture of polymyxins A, B, C, and D produced byBacillus polymyxa. It was later separated into the major component, B1, and the minor component, B2. Polymyxin B is a basic polypeptide and shows strong activity against gram-negative bacteria, but its activity against gram-positive bacteria, Mycobacterium, and fungi is weak. Because of its toxicity, it is used carefully by intramuscular injection for resistant Pseudomonas aeruginosa infections, e.g., sepsis. Polymyxin B is used orally to sterilize the gut in leukemic patients, intraspinally for meningitis, or topically.

Uses

Antibacterial Aerosporin.

Definition

ChEBI: A polymyxin having a 6-methylheptanoyl group at the amino terminus.

brand name

(GlaxoSmithKline); Poly-Rx (X Gen).

Contact allergens

Active against Gram-negative bacteria, Polymyxin B is a mixture of Polymyxin B1 and B2. Sensitization occurs by topical, ophthalmic, and otic preparations. Cosensitization is frequent with other topical antibiotics like neomycin or bacitracin.

Polymyxin B Supplier

HUBEI MICRO PHARMACEUTICAL Gold
Tel
18627055345
Email
info@micropharm.cn
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Email
3007715519@qq.com
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Email
waley188@sohu.com
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Email
sales@sunlidabio.com