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D-Norleucine

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D-Norleucine Basic information

Product Name:
D-Norleucine
Synonyms:
  • D-Norleucine
  • H-D-2-AMINOCAPROIC ACID
  • H-D-ACPO(2)-OH
  • H-D-AHX(2)-OH
  • H-D-NLE-OH
  • H-D-NORLEUCINE
  • D-2-AMINO CAPROIC ACID
  • D-2-AMINOHEXANOIC ACID
CAS:
327-56-0
MF:
C6H13NO2
MW:
131.17
EINECS:
206-320-9
Product Categories:
  • Leucine [Leu, L]
  • Amino Acids
  • AMINO ACIDS
  • Amino Acid Derivatives
Mol File:
327-56-0.mol
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D-Norleucine Chemical Properties

Melting point:
≥300 °C
alpha 
[α]D20 -23.0~-25.0゜ (c=4, HCl)
Boiling point:
234.0±23.0 °C(Predicted)
Density 
1.1720 (estimate)
refractive index 
-23 ° (C=4.5, 6mol/L HCl)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.55±0.24(Predicted)
form 
powder to crystal
color 
White
Water Solubility 
15.75g/L(19 ºC)
Merck 
14,6706
BRN 
1721749
InChIKey
LRQKBLKVPFOOQJ-RXMQYKEDSA-N
CAS DataBase Reference
327-56-0(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29224999

MSDS

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D-Norleucine Usage And Synthesis

Chemical Properties

white to off-white crystalline powder or flakes

Uses

D-Norleucine is used for the synthesis of Thailandepsin B, a bicyclic depsipeptide histone deacetylase inhibitor.

Definition

ChEBI: D-norleucine is the D-enantiomer of 2-aminohexanoic acid. It is an enantiomer of a L-norleucine. It is a tautomer of a D-norleucine zwitterion.

Purification Methods

Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]

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