MPEG16-Propyne CAS#: 2169967-47-7

MPEG16-Propyne Basic information

Product Name:

MPEG16-Propyne

Synonyms:

MPEG16-Propyne
2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne
Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane
mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne

CAS:

2169967-47-7

MF:

C36H70O17

MW:

774.93

Mol File:

2169967-47-7.mol

More

Less

MPEG16-Propyne Usage And Synthesis

Biological Activity

Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

MPEG16-PropyneSupplier

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Email: service@chempep.com

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Email: info@amateksci.com

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840
Email: psaitong@jm-bio.com