Basic information Safety Supplier Related

MPEG16-Propyne

Basic information Safety Supplier Related

MPEG16-Propyne Basic information

Product Name:
MPEG16-Propyne
Synonyms:
  • MPEG16-Propyne
  • 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne
  • Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane
  • mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne
CAS:
2169967-47-7
MF:
C36H70O17
MW:
774.93
Mol File:
2169967-47-7.mol
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MPEG16-Propyne Usage And Synthesis

Biological Activity

Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

MPEG16-PropyneSupplier

ChemPep, Inc.
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Amatek Scientific Co. Ltd.
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0512-56316828
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
Affinity（Wuhan）Ltd.
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15841022315
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sales@affinitytech.cn
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