6-Hydroxycoumarin
6-Hydroxycoumarin Basic information
- Product Name:
- 6-Hydroxycoumarin
- Synonyms:
-
- 2H-1-Benzopyran-2-one, 6-hydroxy-
- 6-HYDROXY-2H-CHROMEN-2-ONE
- 6-HYDROXYCOUMARIN
- 6-Hydroxy-2H-chromen-2-one 97%
- 6-Hydroxy-2H-1-benzopyran-2-one
- 6-hydroxychromen-2-one
- HYDROXYCOUMARIN, 6-(RG)
- 6-Hydroxycoumarin 97%
- CAS:
- 6093-68-1
- MF:
- C9H6O3
- MW:
- 162.14
- Product Categories:
-
- Coumarins
- Fused Ring Systems
- Building Blocks
- Heterocyclic Building Blocks
- Mol File:
- 6093-68-1.mol
6-Hydroxycoumarin Chemical Properties
- Melting point:
- 249-253 °C (lit.)
- Boiling point:
- 248.82°C (rough estimate)
- Density
- 1.2500
- refractive index
- 1.5380 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 8.92±0.20(Predicted)
- form
- Solid
- color
- White to yellow
- λmax
- 349nm(EtOH)(lit.)
- LogP
- 0.650 (est)
- CAS DataBase Reference
- 6093-68-1(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29322010
MSDS
- Language:English Provider:SigmaAldrich
6-Hydroxycoumarin Usage And Synthesis
Description
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity.
Occurrence
6-Hydroxycoumarin is a natural product found in Grevillea robusta and Amburana cearensis with data available.
Uses
6-Hydroxycoumarin (cas# 6093-68-1) is a compound useful in organic synthesis.
Preparation
(1) synthesis of 6-aminocoumarins：In polar solvent, using 6- nitroscumarin as raw material, using hydrazine hydrate as hydrogen Source, is reducing catalyst using ferric chloride (FeCl36H2O), at ambient pressure reduces 6-nitroscumarin, prepare 6- aminocoumarins；
(2) synthesis of 6-Hydroxycoumarins：In sulfuric acid solution, one-step method is by 6-aminocoumarins after diazo-reaction Direct hydrolysis, prepares 6-Hydroxycoumarins in high yield.
The preparation method of 6 Hydroxycoumarins
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6-Hydroxycoumarin(6093-68-1)Related Product Information
- FRAXIN
- 6-HYDROXY-4-METHYLCOUMARIN
- 7-hydroxycoumarin-6-yl beta-d-glucopyranoside
- Scopoletin
- SCOPARONE
- 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN
- FRAXIDIN
- Esculetin
- 4-METHYLESCULETIN
- 6,7-DIMETHOXY-4-METHYLCOUMARIN
- 7,8-DIHYDROXY-6-METHOXYCOUMARIN
- ESCULETIN DIBENZYL ETHER
- 6-HYDROXY-7-METHOXYCOUMARIN
- 3-(α-acetonyl-2-furylmethyl)-4-hydroxycoumarin
- 5,7-DIHYDROXYCOUMARIN
- DICUMAROL
- 3-(A-ACETONYLBENZYL)-4-HYDROXYCOUMARIN, SODIUM CLAT,3-(α-Acetonylbenzyl)-4-hydroxycoumarin, sodium salt
- 7,8-Dihydroxycoumarin