9-Aminoacridine hydrochloride hydrate Chemical Properties

Melting point:

300 °C(lit.)

storage temp. 

Store below +30°C.

solubility 

3.3g/l

form 

powder to crystal

color 

Light yellow to Yellow to Orange

Water Solubility 

Soluble in water (3.3 g/L) at 20°C.

Sensitive 

Hygroscopic

Merck 

14,407

BRN 

3707637

Stability:

Stable. Incompatible with strong oxidizing agents, strong bases, acid anhydrides.

CAS DataBase Reference

52417-22-8(CAS DataBase Reference)

EPA Substance Registry System

9-Aminoacridine hydrochloride monohydrate (52417-22-8)

Safety Information

Hazard Codes 

T,Xn,F

Risk Statements 

68-23/24/25-40-20/21/22-15-10-25

Safety Statements 

22-24/25-45-43-36/37/39-36-7/8

RIDADR 

2811

WGK Germany 

3

RTECS 

AR6850000

TSCA 

Yes

HS Code 

2933 99 80

HazardClass 

6.1

PackingGroup 

III

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

9-Aminoacridine hydrochloride hydrate Usage And Synthesis

Chemical Properties

yellow powder

Uses

9-Aminoacridine hydrochloride is a known mutagen and DNA modifier.

Uses

Mutagen.

General Description

Bright yellow to yellow-green powder.

Air & Water Reactions

9-Aminoacridine hydrochloride hydrate is sensitive to prolonged exposure to air . Slightly soluble in water.

Reactivity Profile

Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Health Hazard

SYMPTOMS: Symptoms of exposure to 9-Aminoacridine hydrochloride hydrate include irritation of the gastrointestinal mucosa, nausea and vomiting.

Fire Hazard

Flash point data are not available for 9-Aminoacridine hydrochloride hydrate, but 9-Aminoacridine hydrochloride hydrate is probably combustible.

Purification Methods

Recrystallise it from boiling H2O (charcoal; 1g in 300 mL) to give pale yellow crystals with a neutral reaction. It is one of the most fluorescent substances known. At 1:1000 dilution in H2O it is pale yellow with only a faint fluorescence, but at 1:100,000 dilution it is colourless with an intense blue fluorescence. [Albert & Ritchie Org Synth Coll Vol III 53 1955; Falk & Thomas Pharm J 153 158 1944, Beilstein 22 H 463, 21 II 280, 21 III/IV 4174.] See previous entry for the free base.

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