Thalidomide-linker 15
Thalidomide-linker 15 Basic information
- Product Name:
- Thalidomide-linker 15
- Synonyms:
-
- Thalidomide-linker 15
- Thalidomide-O-amido-C6-NH2 hydrochloride
- -oxyacetamide-alkylC6-amine
- N-(6-Aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
- ThalidomideOamidoC6NH2 hydrochloride,Inhibitor,inhibit,E3 Ligase Ligand-Linker Conjugates,Thalidomide-O-amido-C-6-NH2 hydrochloride,Thalidomide O amido C6 NH2 hydrochloride
- Thalidomide 4'-oxyacetamide-alkylC6-amine
- Thalidomide-O-amido-C6-NH2 HCl
- Acetamide, N-(6-aminohexyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)
- CAS:
- 2376990-31-5
- MF:
- C21H27ClN4O6
- MW:
- 466.92
- Mol File:
- 2376990-31-5.mol
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Thalidomide-linker 15 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
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Thalidomide-linker 15 Usage And Synthesis
Uses
Thalidomide-O-amido-C6-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1
Thalidomide-linker 15Supplier
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Hunan HuaTeng Pharmaceutical Co., Ltd.,
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Thalidomide-linker 15(2376990-31-5)Related Product Information
- E3 Ligase Ligand-Linker Conjugates 24 (TFA)
- E3 Ligase Ligand-Linker Conjugates 21
- E3 Ligase Ligand-Linker Conjugates 19
- Thalidomide-O-amido-C4-NH2 hydrochloride
- Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
- Thalidomide-O-amido-C8-NH2 hydrochloride
- Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
- Thalidomide-O-amido-PEG4-azide
- Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
- N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
- E3 Ligase Ligand-Linker Conjugates 20
- Thalidomide-linker 14
- Thalidomide-linker 13
- NA
- Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-