2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Chemical Properties

Melting point:

66-68 °C (lit.)

Boiling point:

166.1±35.0 °C(Predicted)

Density 

1.56±0.1 g/cm3(Predicted)

pka

-14.32±0.28(Predicted)

form 

crystalline powder

color 

White

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

2933399990

MSDS

• Language:English Provider:SigmaAldrich

2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Usage And Synthesis

Uses

2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile may be used in the preparation of 2-anilino-3,5,6-trifluoroisonicotinonitrile.

General Description

2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile is a perfluorinated heteroaromatic compound. 2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (tetrafluoro-4-cyanopyridine) reacts with 1,3-dicarbonyl systems to yield the corresponding [5,6]-ring fused furo derivatives. 2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (4-cyanotetrafluoropyridine) reacts with amidines to yield [6,6]-fused pyrimidinopyridine system via nucleophilic substitution at the C-3 position of the pyridine ring followed by intramolecular cyclization onto the pendant cyano group. Reaction of 2,3,5,6-tetrafluoro-4-pyridinecarbonitrile (4-cyanotetrafluoropyridine) with sulfur centred nucleophiles has been reported.

2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE(16297-07-7)Related Product Information

• 2,3-Difluoropyridine
• 2,3,6-TRIFLUOROPYRIDINE
• 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
• 2-FLUOROISONICOTINONITRILE
• 3,5-Difluoropyridine
• 2,3,5,6-Tetrafluoropyridine
• 4-Cyanopyridine
• 2,5-Difluoropyridine
• 3-Fluoro-4-methylpyridine
• 2,6-Difluoropyridine
• 3-Fluoropyridine
• 2-Fluoropyridine
• 2 3 5 6-TETRAFLUORO-4-METHYLPYRIDINE 9&
• 2,3,5-Trifluoropyridine
• 2-Fluoro-4-methylpyridine
• 2,6-DIFLUORO-4-CYANO-PYRIDINE
• 3-Fluoropyridine-4-carbonitrile