Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Basic information
- Product Name:
- Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
- Synonyms:
-
- pybop?/td>
- BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHYLAMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE)
- (BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE
- BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINPHOSPHONIUM HEXAFLUOROPHOSPHATE
- Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
- BENZOTRIAZOLE-1-YL-OXY-TRIS-DIMETHYLAMINOPHOPHONIUM
- BENZOTRIAZOL-1-YLOXYTRIS(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE
- BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOPHONIUM HEXAFLUOROPHOSPHATE
- CAS:
- 128625-52-5
- MF:
- C18H28F6N6OP2
- MW:
- 520.39
- EINECS:
- 603-290-2
- Product Categories:
-
- Peptide Coupling Reagents
- Peptide coupling agents
- Amino Acid Derivatives
- Biochemistry
- Condensation & Active Esterification
- Coupling Reactions (Peptide Synthesis)
- Peptide Synthesis
- Phosphonium Compounds
- Synthetic Organic Chemistry
- Peptide
- Miscellaneous Reagents
- Aromatics
- peptides
- Mol File:
- 128625-52-5.mol
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Chemical Properties
- Melting point:
- 154-156 °C (dec.)(lit.)
- Density
- 1.438 at 20℃
- vapor pressure
- 0-0Pa at 20-50℃
- storage temp.
- 2-8°C
- solubility
- methanol: 25 mg/mL, clear
- form
- Fine Crystalline Powder
- color
- White to off-white
- Sensitive
- Moisture Sensitive
- BRN
- 3584612
- InChIKey
- BYCLGHOAELJLOF-UHFFFAOYSA-M
- LogP
- -0.3 at 26℃ and pH3.5-3.7
- CAS DataBase Reference
- 128625-52-5(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 37/38-44-36/37/38
- Safety Statements
- 26-36-24/25-37/39
- RIDADR
- UN 1325 4.1/PG 2
- WGK Germany
- 3
- F
- 8-10-21
- Hazard Note
- Irritant
- HS Code
- 29339980
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
One of the most convenient coupling reagents for peptide synthesis without carcinogenic by-products. It replaces BOP reagent. This is especially suitable for solid-phase peptide synthesis, avoids racemization.
Uses
1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl) phosphonium hexafluorophosphate is a peptide coupling reagent utilized in solid phase peptide synthesis. It is also used as a substitute for the (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.
Uses
Reagent for:
Synthesis of single labeled oligonucleotides that fluoresce upon matched hybridization
Generation of endocrine disruptor chemical binders
Cycloaddition to template-assembled multivalent peptide conjugates
General Description
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphateSupplier
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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate(128625-52-5)Related Product Information
- Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
- DEPBT
- TSTU
- 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate
- Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
- Diphenylphosphoryl azide
- 1H-Benzotriazole
- Hexafluorophosphoric acid
- Potassium hexafluorophosphate
- Lithium hexafluorophosphate
- Sodium hexafluorophosphate
- Hexafluorophosphate
- TRIS(DIETHYLAMINO)PHOSPHINE
- 1-Hydroxybenzotriazole hydrate
- 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
- Hexamethylphosphorous triamide
- Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate