ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Phosphine ligand > Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Basic information
- Product Name:
- Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
- Synonyms:
-
- PYBROP
- PYBROP(R)
- PYBROP(TM)
- BROMOTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE
- BROMO-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE
- BROMO-TRIS-PYRROLIDINO-PHOSPHONIUM HEXFLUOROPHOSPHATE
- Pybrop(Bromo-Tris-PyrrolidinophosphoniumHexafluorophosphate)
- PyBroP\(rg
- CAS:
- 132705-51-2
- MF:
- C12H24BrF6N3P2
- MW:
- 466.19
- EINECS:
- 620-834-4
- Product Categories:
-
- Peptide
- Coupling Reagent
- Peptide Coupling Reagents
- Mol File:
- 132705-51-2.mol
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Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Chemical Properties
- Melting point:
- 100 °C
- storage temp.
- -20°C
- solubility
- DMF: 0.4 g/mL, clear
- form
- Powder
- color
- White to off-white
- Water Solubility
- moderately soluble
- Sensitive
- Moisture Sensitive
- BRN
- 7845702
- Stability:
- Moisture Sensitive
- InChIKey
- CYKRMWNZYOIJCH-UHFFFAOYSA-N
- CAS DataBase Reference
- 132705-51-2(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38-34
- Safety Statements
- 26-36-45-36/37/39-27
- WGK Germany
- 3
- F
- 10-21
- HS Code
- 2933 99 80
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Usage And Synthesis
Chemical Properties
white to off-white powder
Uses
A stable reagent for the coupling of N-Methylamino acids in peptide synthesis.
Uses
It can be used as a coupling reagent:
- For Suzuki–Miyaura cross-coupling of phenols and arylboronic acids to synthesize biaryls and heterobiaryls.
- To functionalize pyrimidines (synthesized from 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via the Kappe dehydrogenation) by using various nucleophiles.
- To synthesize formamidines by coupling with various primary amines and N,N-diisopropylethylamine.
It can also be used as an activating reagent:
- For the activation of C-OH bond in tautomerizable heterocycles to form the phosphonium salt which aids the Sonogashira coupling of heterocycles with various alkynes.
- For the one–pot activation of C-O bond in phenols and further coupling reaction with phosphine oxide or phosphite to form C-P bonds.
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphateSupplier
Suzhou Highfine Biotech Co., Ltd Gold
- Tel
- 0512-68311833 13962195826
- wuhao@highfine.com
Jinan Kabotang Biological Technology Co.,Ltd. Gold
- Tel
- 0531-61320525 15866703830
- 495745175@qq.com
Shaoxing Jiufu New Material Technology Co., LTD Gold
- Tel
- 0575-87095566 18067860628
- sales@sxjiufu.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
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Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate(132705-51-2)Related Product Information
- Potassium hexafluorophosphate
- BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE)
- Hexafluorophosphoric acid
- Lithium hexafluorophosphate
- Tris(hydroxymethyl)aminomethane
- BIS-Tris
- Ammonium hexafluorophosphate
- Tricine
- 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate
- Diphenylphosphoryl azide
- TRIS(DIETHYLAMINO)PHOSPHINE
- Hexamethylphosphorous triamide
- Bromotris(dimethylamino)phosphonium hexafluorophosphate
- Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
- Bromine
- TRIS BUFFER SOLUTION PH 8.5, 1 L
- bromo-Dragonfly