CYTIDINE 5'-MONOPHOSPHO-N- Chemical Properties

Density 

2.02±0.1 g/cm3(Predicted)

storage temp. 

-20°C

pka

1.30±0.50(Predicted)

BRN 

4224251

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

3

F 

10-21

CYTIDINE 5'-MONOPHOSPHO-N- Usage And Synthesis

Uses

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used:

• as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis in Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts,
• As a substrate for the enzymatic sialylation of G2 glycoforms, resialylation assay,
• in in-vitro sialyltransferase assay

Definition

ChEBI: CMP-N-acetyl-beta-neuraminic acid is a nucleotide sugar used as a donor by glycosyltransferases for the synthesis of sugar chains It has a role as a mouse metabolite. It is functionally related to a N-acetyl-beta-neuraminic acid. It is a conjugate acid of a CMP-N-acetyl-beta-neuraminate(2-).

General Description

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is a sugar-nucleotide produced by CMP-Neu5Ac synthetase from CTP and Neu5Ac.

Biochem/physiol Actions

Cytidine-5′-monophospho-N-acetylneuraminic acid (CMP-Sialic acid) is a substrate for sialyltransferases. It is used for the enzymatic sialylation of glycans.

CYTIDINE 5'-MONOPHOSPHO-N-(3063-71-6)Related Product Information

• GDP-ALPHA-D-MANNOSE, DISODIUM SALT
• Guanosine 5′-diphospho-β-L-fucose
• UDP-ALPHA-D-N-ACETYLGALACTOSAMINE, DISODIUM SALT
• TRISIALOGANGLIOSIDE GT1B 3NA
• GANGLIOSIDE GM2 SODIUM SALT
• GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE
• DISIALOGANGLIOSIDE GD1B 2NA
• DISIALOGANGLIOSIDE GD3
• GANGLIOSIDE GD1A DISODIUM SALT
• N-Acetylneuraminic acid
• Neuraminidase
• N-Acetyl-β-neuraminic acid methyl ester monohydrate
• 3'-SIALYLLACTOSE
• CYTIDINE 5'-MONOPHOSPHO-N-ACETYLNEURAMINIC ACID SODIUM SALT
• CYTIDINE-5'-MONOPHOSPHO-N-ACETYLNEURAMINIC ACID DISODIUM SALT
• CYTIDINE 5'-MONOPHOSPHO[14C]SIALIC ACID, AMMONIUM SALT
• CMP-NeuAc-(NeuAc-alpha-2-8)n sialyltransferase
• cytidine 5'-monophospho-(N-acetylneuraminyl-2-8-N-acetylneuraminic acid)