Basic information Description References Safety Supplier Related
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Leucine derivatives >  Methoxycarbonyl-L-tert-leucine

Methoxycarbonyl-L-tert-leucine

Basic information Description References Safety Supplier Related

Methoxycarbonyl-L-tert-leucine Basic information

Product Name:
Methoxycarbonyl-L-tert-leucine
Synonyms:
  • MOC-L-tert.Leucine
  • (S)-2-Methoxycarbonylamino-3,3-dimethylbutyric acid
  • Methoxycarbonyl-L-tert-leucine
  • N-(Methoxycarbonyl)-3-methyl-L-valine
  • N-Methoxycarbonyl-tert-leucine
  • Atazanavir related coMpound A
  • MOC-L-tert. Leucin
  • L-Valine,N-(Methoxycarbonyl)-3-Methyl-
CAS:
162537-11-3
MF:
C8H15NO4
MW:
189.21
EINECS:
1308068-626-2
Product Categories:
  • Amino Acid Derivatives
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Chiral Reagents
Mol File:
162537-11-3.mol
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Methoxycarbonyl-L-tert-leucine Chemical Properties

Melting point:
1090C
Boiling point:
320.9±25.0 °C(Predicted)
Density 
1.126±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in ethyl acetate and methanol.
pka
4.46±0.10(Predicted)
form 
powder
InChIKey
NWPRXAIYBULIEI-RXMQYKEDSA-N
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Safety Information

HS Code 
2933399090
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Methoxycarbonyl-L-tert-leucine Usage And Synthesis

Description

Methoxycarbonyl-L-tert-leucine is a kind of amino acid deriviative. It is a very useful intermediate for efficient synthesis of the HIV protease inhibitor BMS-232632 as well as atazanavir bisulfate. 

References

Zhongmin Xu, †, et al. "Process Research and Development for an Efficient Synthesis of the HIV Protease Inhibitor BMS-232632." Organic Process Research & Development 6.3(2002):323-328.
Simhadri, Srinivas. "Process for the preparation of atazanavir bisulfate." (2016).
https://www.alfa.com/en/search/?q=14328-63-3

Chemical Properties

White Solid

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