Flopropione Chemical Properties

Melting point:

177°C

Boiling point:

275.56°C (rough estimate)

Density 

1.2481 (rough estimate)

refractive index 

1.4500 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in DMSO

form 

powder to crystal

pka

7.49±0.45(Predicted)

color 

White to Orange to Green

Merck 

14,4106

LogP

2.600 (est)

CAS DataBase Reference

2295-58-1(CAS DataBase Reference)

NIST Chemistry Reference

Flopropione(2295-58-1)

EPA Substance Registry System

1-Propanone, 1-(2,4,6-trihydroxyphenyl)- (2295-58-1)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

RTECS 

UH4429100

HS Code 

2914.50.3000

Flopropione Usage And Synthesis

Uses

antispasmodic

Preparation

Preparation by reaction of propionitrile with phlo-roglucinol (Hoesch reaction);
Preparation by reaction of propionic anhydride with phloroglucinol
in the presence of concentrated sulfuric acid (one drop) at 130° for 5 min ? (65%)
in the presence of Amberlite IR-120 (cation exchange resin sulfonic acid ? type) at 160° for 2–3 h (42%). N.B.: Zeokarb 225 was found to be as effective
in the presence of boron trifluoride etherate at 10° (62–65%)
Preparation by reaction of propionyl chloride with phloroglucinol
in the presence of aluminium chloride in nitrobenzene/carbon disulfide ? solution (76%), in nitrobenzene at 60° (55%) or without solvent at 50° (70%)
in the presence of boron trifluoride etherate at 10° (compound ? 3) (62–65%).

Definition

ChEBI: Flopropione is an organic molecular entity.

Flopropione(2295-58-1)Related Product Information

• Trimethylolpropane
• Calcium pyruvate
• Diphenylsilanediol
• Tris(hydroxymethyl)aminomethane
• 3'-Hydroxypropiophenone
• Acetylacetone
• Phenylfluorone
• 2'-Hydroxyacetophenone
• 4'-Hydroxyacetophenone
• Triphenylphosphine
• Benzoylcyclohexane
• Propane
• DIPHENYLCYCLOPROPENONE
• Pyruvic acid
• Diacetone Alcohol
• Phenylacetone
• LUTEONE
• Propiophenone