GLDH Chemical Properties

storage temp. 

-20°C

form 

solution (viscous)

color 

amber

EPA Substance Registry System

Dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) (9029-12-3)

Safety Information

WGK Germany 

3

F 

3-10

GLDH Usage And Synthesis

Uses

L-Glutamic Dehydrogenase was used to catalyzes the conversion of isocitrate into a-ketoglutarate and carbon dioxide.

Biochem/physiol Actions

Mammalian forms of this enzyme, including this bovine form, can use either NADP(H) or NAD(H) as coenzymes. L-glutamic dehydrogenase plays a unique role in mammalian metabolism. The reverse reaction catalyzed by this enzyme is the only pathway by which ammonia can become bound to the α-carbon atom of an α-carboxylic acid and thus, is the only source of de novo amino acid synthesis in mammalian species. The bovine enzyme is characterized by three sets of properties: It has a reversible concentration-dependent association, producing higher molecular weight forms.Forms tight enzyme-reduced coenzyme-substrate ternary complexes whose rates of dissociation modulate the steady-state reaction rates.Exhibits a wide variety of effects from the binding of any of a number of nucleotide modifiers.L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutarate.

GLDH(9029-12-3)Related Product Information

• Benzyl isocyanide
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• Tosylmethyl isocyanide
• Aluminum acetylacetonate
• Tris(2,4-pentanedionato)chroMiuM(III)
• N-BUTYLISOCYANIDE
• SALCOMINE
• Cupric acetylacetonate
• TERT-BUTYL ISOCYANIDE
• COBALT(II) ACETYLACETONATE
• PHENYLSELENOL
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
• 2,4-PENTANEDIONE, SILVER DERIVATIVE
• Ethyl isocyanoacetate
• Ferric acetylacetonate
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• Glutamate dehydrogenase from bovine liver