GD2-GANGLIOSIDE
GD2-GANGLIOSIDE Basic information
- Product Name:
- GD2-GANGLIOSIDE
- Synonyms:
-
- (2S,4S,5R)-6-((1S,2R)-2-((2S,4S,5R)-2-carboxy-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-yloxy)-1,3-dihydroxypropyl)-2-((2S,3R,4R,5S,6R)-2-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-dodecanamido-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-5-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxytetrahydro-2H-pyran-2-carboxylic acid
- Ganglioside GD2 (d18:1/12:0)
- (2S,4S,5R)-2-((1S,2R)-1-((3R,4S,6S)-6-carboxy-3-ethanamido-6-((2R,3S,4R,5R,6S)-3-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-6-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-hexadecanamido-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-5-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-hydroxytetrahydro-2H-pyran-2-yl)-1,3-dihydroxypropan-2-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid
- Ganglioside GD2 (d18:1/16:0)
- (2S,4S,5R)-6-((1S,2R)-2-((2S,4S,5R)-2-carboxy-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-yloxy)-1,3-dihydroxypropyl)-2-((2S,3R,4R,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-octadecanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-5-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxytetrahydro-2H-pyran-2-carboxylic acid
- Ganglioside GD2 (d18:1/18:0)
- (2S,4S,5R)-6-((1S,2R)-2-((2S,4S,5R)-2-carboxy-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-yloxy)-1,3-dihydroxypropyl)-2-((2S,3R,4R,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-icosanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-5-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxytetrahydro-2H-pyran-2-carboxylic acid
- Ganglioside GD2 (d18:1/20:0)
- CAS:
- 65988-71-8
- MF:
- C74H134N4O32
- MW:
- 1591.86336
- Product Categories:
-
- Acidic glycosphingolipids
- Cell Signaling and Neuroscience
- Gangliosides
- GangliosidesGlycan Component Classes
- GangliosidesSphingolipids
- Glycosphingolipids
- Lipids in Cell Signaling
- Mol File:
- 65988-71-8.mol
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GD2-GANGLIOSIDE Chemical Properties
- storage temp.
- −20°C
- form
- lyophilized powder
MSDS
- Language:English Provider:SigmaAldrich
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GD2-GANGLIOSIDE Usage And Synthesis
Chemical Properties
lyophilized powder
Uses
Disialoganglioside-GD2 from bovine brain has been used:
- in the ganglioside- enzyme-linked immunosorbent assay (ELISA)
- in capture ELISA with anti-GD2 antibody (ch14.18)
- as a control to test its effect on reactivating autophagy in primary fibroblasts
General Description
Disialoganglioside GD2 is a cell surface-associated glycosphingolipid, which comprises sialic acid moiety and is regarded as a carbohydrate antigen.. It is expressed in the skin melanocytes, central and peripheral nervous system.
Biochem/physiol Actions
Disialoganglioside GD2 is expressed in neuroblastoma, melanoma and small cell lung cancer. It is an immunotherapeutic target and is also regarded as a tumor-associated antigen. GD2 may favor cell migrationin tumors by promoting cell growth, as well as extracellular matrix component attachment.
GD2-GANGLIOSIDESupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Yichang Zhongyitai Trading Co., Ltd.
- Tel
- 0717-6449896 13886658719
- root@zhongyitai.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Alfa Chemistry
- Tel
- 1-516-6625404
- support@alfa-chemistry.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
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GD2-GANGLIOSIDE(65988-71-8)Related Product Information
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