1,6-Dihydroxyeriolanolide Chemical Properties

Melting point:

175.1-177.0℃

Boiling point:

477.4±45.0 °C(Predicted)

Density 

1.17±0.1 g/cm3 (20 ºC 760 Torr)

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Cryst.

pka

13.71±0.60(Predicted)

color 

White to off-white

1,6-Dihydroxyeriolanolide Usage And Synthesis

Uses

Britannilactone(Desacetylinulicin) is a methanol extract of the dried flower of Inula britannica L. IC50 value: Target: A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively [1].

References

[1] Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37(5):567-74. DOI:10.1007/s12272-013-0302-4

1,6-Dihydroxyeriolanolide(33620-72-3)Related Product Information

• Curdione
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• alpha-Cyperone
• Furanodienone
• inulicin
• ERGOLIDE
• beta-Eudesmol
• 1-Caffeoylquinic acid
• CYNARIN
• Curzerene
• 1,6-O,O-diacetylbritannilactone
• 1-O-acetyl Britannilactone
• Curzerenone
• β-Caryophyllene
• Artemether
• Cynarin
• Curcumenol
• Curcumol