3'-(Trifluoromethyl)acetophenone Chemical Properties

Boiling point:

198-200 °C(lit.)

Density 

1.235 g/mL at 25 °C(lit.)

vapor pressure 

35Pa at 25℃

refractive index 

n20/D 1.4611(lit.)

Flash point:

183 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

Specific Gravity

1.235

color 

Colorless to Red to Green

Water Solubility 

620mg/L at 25℃

BRN 

640151

InChIKey

ABXGMGUHGLQMAW-UHFFFAOYSA-N

LogP

2.55 at 25℃

CAS DataBase Reference

349-76-8(CAS DataBase Reference)

NIST Chemistry Reference

3-CF3-C6H4-COCH3(349-76-8)

EPA Substance Registry System

Ethanone, 1-[3-(trifluoromethyl)phenyl]- (349-76-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

1

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29147090

MSDS

• Language:English Provider:3-Acetylbenzotrifluoride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3'-(Trifluoromethyl)acetophenone Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID

Uses

3''-?(Trifluoromethyl)?acetophenone is a reagent used in the stabilization of endosomal-toll-like receptor TRL8 creating a sort of inhibitory activity.

General Description

Asymmetric catalytic addition of ethyl groups to 3′-(trifluoromethyl)acetophenone catalyzed by ligands derived from trans-1,2-diaminocyclohexane and camphor sulfonyl chloride has been reported. Phenylation of 3′-(trifluoromethyl)acetophenone in the presence of dihydroxy bis(sulfonamide) ligand (enantioselective catalyst), titanium tetraisopropoxide and diphenylzinc has been investigated.

3'-(Trifluoromethyl)acetophenone(349-76-8)Related Product Information

• 4-(TRIFLUOROMETHYL)PHENYLACETONITRILE
• 4'-(Trifluoromethoxy)acetophenone
• 3-(Trifluoromethyl)phenylacetone
• 3-Trifluoromethylphenol
• 2-(Trifluoromethyl)benzoic acid
• 3'-Methylacetophenone
• 3-Nitroacetophenone
• 3-(Trifluoromethyl)benzaldehyde
• 3-(Trifluoromethyl)benzoyl chloride
• Trifluoroacetophenone
• Trifluoromethanesulfonic acid
• Chalcone
• PHENYL VALERATE
• Acetophenone
• 3-(Trifluoromethyl)benzoic acid
• 4-Fluoroacetophenone
• 4'-(Trifluoromethyl)acetophenone
• 3-Aminoacetophenone