CREATINE AMIDINOHYDROLASE Chemical Properties

storage temp. 

2-8°C

form 

lyophilized powder

color 

white

EPA Substance Registry System

Creatinase (37340-58-2)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich

CREATINE AMIDINOHYDROLASE Usage And Synthesis

Uses

Creatine amidinohydrolase is a clinically important enzyme used in the determination of creatinine in blood and urine.

General Description

Creatinase is a homodimer that catalyzes hydrolysis of creatine. It consists of two monomer subunit and two defined domains; N and C terminal domains. C terminal fold have both the α helices and anti-parallel β sheet within two structurally similar domains. In between these two domains, there is a sulfhydryl group that acts as active site and the activity is metal independent.

Biochem/physiol Actions

Creatinase is a homodimer with subunit molecular weights of approximately 45 kDa. It catalyzes the hydrolysis of creatine, in the presence of H2O, to form urea and sarcosine.

CREATINE AMIDINOHYDROLASE(37340-58-2)Related Product Information

• METHYL ISOCYANOACETATE
• Tris(2,4-pentanedionato)chroMiuM(III)
• PHENYLSELENOL
• Cupric acetylacetonate
• Benzyl isocyanide
• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• TERT-BUTYL ISOCYANIDE
• 2,4-PENTANEDIONE, SILVER DERIVATIVE
• COBALT(II) ACETYLACETONATE
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
• Aluminum acetylacetonate
• N-BUTYLISOCYANIDE
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
• Tosylmethyl isocyanide
• SALCOMINE
• Ethyl isocyanoacetate
• Sarcosine