Tos-PEG2-t-butyl ester
Tos-PEG2-t-butyl ester Basic information
- Product Name:
- Tos-PEG2-t-butyl ester
- Synonyms:
-
- Tos-PEG2-t-butyl ester
- Tos-PEG1-CH2CH2COOtBu
- Tos-PEG2-Boc
- tert-Butyl 3-(2-(tosyloxy)ethoxy)propanoate
- Tos-PEG1-CH2CH2COOtBu/Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
- Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
- tert-butyl 3-[2-(4-methylphenyl)sulfonyloxyethoxy]propanoate
- Tos-PEG1-t-butyl ester
- CAS:
- 1309666-78-1
- MF:
- C16H24O6S
- MW:
- 344.42
- Mol File:
- 1309666-78-1.mol
More
Less
Tos-PEG2-t-butyl ester Chemical Properties
- Boiling point:
- 460.6±30.0 °C(Predicted)
- Density
- 1.164±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Solid
- color
- White to off-white
More
Less
Tos-PEG2-t-butyl ester Usage And Synthesis
Description
Tos-PEG2-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG2-t-butyl esterSupplier
Nanjing Junnahe Biopharmaceutical Co., Ltd
- Tel
- 025-58367986 17351780683
- amy.xiang@ally-chem.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Jinan elephant international trading co., LTD
- Tel
- 13006575422@163.com
Shanghai Yihe Biological Technology Co., Ltd.
- Tel
- 021-68882955 17721395025
- 2423903095@qq.com
Amatek Scientific Co. Ltd.
- Tel
- 0512-56316828
- info@amateksci.com
More
Less
Tos-PEG2-t-butyl ester(1309666-78-1)Related Product Information
- Tos-PEG3-t-butyl ester
- Tos-PEG4-CH2CO2H
- Tos-PEG4-t-butyl ester
- Tos-PEG6-t-Butyl ester
- Tos-PEG3-CH2CO2tBu
- Tos-PEG5-CH2CO2H
- Tos-PEG5-CH2CO2t-butyl ester
- Tos-PEG5 t-butyl ester
- Tos-PEG9-t-butyl ester
- Tos-PEG7-t-butyl ester
- Tos-PEG10-CH2CH2COOtBu
- Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)
- Tos-PEG1-COOtBu
- Tos-PEG8-COOtBu
- TOS-PEG5-THP
- Tos-PEG13-t-butyl ester
- TETRAETHYLENE GLYCOL DI-P-TOSYLATE
- Tri(Ethylene Glycol) DI-P-Toluenesulfonate