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O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

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O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine Basic information

Product Name:
O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine
Synonyms:
  • HYDROXYLAMINE, O-(TETRAHYDRO-2H-PYRAN-2-YL)-
  • O-(TETRAHYDRO-2H-PYRAN-2-YL)HYDROXYLAMINE
  • O-(TETRAHYDRO-PYRAN-2-YL)-HYDROXYLAMINE
  • O-(2H-Tetrahydropyran-2-yl)hydroxylamine
  • O-tertrahydroxy-pyran-2-yl-hydroxylamine
  • 2-(Aminooxy)tetrahydro-2H-pyran
  • O-(oxan-2-yl)hydroxylaMine
  • O-(Tetrahydropyran-2-yl)-hydroxylaMine, 95+%
CAS:
6723-30-4
MF:
C5H11NO2
MW:
117.15
EINECS:
628-109-4
Product Categories:
  • Building Blocks
  • Chemical Synthesis
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrans
  • Heterocyclic Building Blocks
Mol File:
6723-30-4.mol
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O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine Chemical Properties

Melting point:
34-37 °C (lit.)
Boiling point:
81 °C/20 mmHg (lit.)
Density 
1.1274 (rough estimate)
refractive index 
1.4206 (estimate)
Flash point:
180 °F
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.28±0.20(Predicted)
form 
Low Melting Solid
color 
White
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29329990

MSDS

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O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine Usage And Synthesis

Chemical Properties

White powder

Uses

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine can be used to treat fibrotic and inflammatory diseases.

Uses

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine is used as an oximation reagent in the synthesis of a marine alkaloid which shows significant inhibitory activity against mycothiol S-conjugate amidase.

General Description

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine (OTX) is an O-substituted hydroxylamine. The coupling of OTX with alkaline gel electrophoresis has been reported to improve the process of detecting single strand breaks (SSBs) in DNA.

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