Basic information Safety Supplier Related

ML-9 HYDROCHLORIDE

Basic information Safety Supplier Related

ML-9 HYDROCHLORIDE Basic information

Product Name:
ML-9 HYDROCHLORIDE
Synonyms:
  • ML-9
  • ML-9 HYDROCHLORIDE
  • 1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HCL
  • 1-(5-CHLORONAPHTHALENE-1-SULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HYDROCHLORIDE
  • 1-(5-CHLORONAPHTHALENE-1-SULFONYL)HOMOPIPERAZINE, HCL
  • 1-(5-CHLORONAPHTHALENESULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE, HYDROCHLORIDE
  • 1-(5-CHLORONAPHTHALENESULFONYL)HOMOPIPERAZINE HYDROCHLORIDE
  • 1-(5-CHLORONAPHTHALENESULPHONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE HYDROCHLORIDE
CAS:
105637-50-1
MF:
C15H18Cl2N2O2S
MW:
361.28
EINECS:
200-258-5
Product Categories:
  • Protein Kinase Inhibitors and Activators
Mol File:
105637-50-1.mol
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ML-9 HYDROCHLORIDE Chemical Properties

Melting point:
196-200
storage temp. 
2-8°C
solubility 
ethanol: 10 mg/mL
form 
powder
color 
white
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Safety Information

WGK Germany 
3
Hazard Note 
Harmful
HS Code 
2935909099

MSDS

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ML-9 HYDROCHLORIDE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular relaxant.

Biological Activity

Selective inhibitor of myosin light chain kinase (MLCK). K i values are 32, 4, and 54 μ M for PKA, MLCK, and PKC respectively. Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca 2+ entry (SOCE).

storage

Desiccate at RT

ML-9 HYDROCHLORIDESupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
VDM Biochemicals
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0330-2528181
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sales@vdmbio.com
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185 18149758185
Email
sales-cpd@caerulumpharma.com