L-CYSTINE DIHYDROCHLORIDE
L-CYSTINE DIHYDROCHLORIDE Basic information
- Product Name:
- L-CYSTINE DIHYDROCHLORIDE
- Synonyms:
-
- (H-CYS-OH)2 2HCL
- (H-CYS-OH)2 HCL
- L-(-)-CYSTINE DIHYDROCHLORIDE
- L-CYSTINE DIHYDROCHLORIDE
- L-Cystine HCl Monohydrate
- L-Cystine dihydrochloride, non-animal source, cell culture tested
- Cystine2HCl,L-
- L-CYSTINE DIHYDROCHLORIDE SALT
- CAS:
- 30925-07-6
- MF:
- C6H13ClN2O4S2
- MW:
- 276.75
- EINECS:
- 250-391-9
- Product Categories:
-
- amino
- Biochemicals Found in Plants
- Nutrition Research
- Amino AcidsNutrition Research
- Amino Acids and Vitamins
- Reagents and Supplements
- Amino acids
- Mol File:
- 30925-07-6.mol
L-CYSTINE DIHYDROCHLORIDE Chemical Properties
- Melting point:
- 228-232℃
- alpha
- [α]D20 -165～-175° (c=1, dil. HCl)
- Density
- 1.518[at 20℃]
- vapor pressure
- 0Pa at 20℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- 0.5 M HCl: 50 mg/mL
- form
- Powder
- color
- White to Pale Yellow
- Odor
- odorless
- biological source
- synthetic
- optical activity
- [α]20/D -174 to -164 °, c =2 in 1 M HCl
- Water Solubility
- Soluble in hydrochloric acid. (0.5 M HCl: 50 mg/mL) Soluble in water.
- InChI
- InChI=1/C6H12N2O4S2.ClH/c7-3(5(9)10)1-13-14-2-4(8)6(11)12;/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12);1H/t3-,4-;/s3
- InChIKey
- IOCJWNPYGRVHLN-QYDODFSFNA-N
- SMILES
- [C@@H](N)(C(=O)O)CSSC[C@H](N)C(=O)O.Cl |&1:0,9,r|
- LogP
- -5.08 at 25℃
- CAS DataBase Reference
- 30925-07-6(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
L-CYSTINE DIHYDROCHLORIDE Usage And Synthesis
Chemical Properties
Solid
Uses
L-Cystine is a sulfur containing non-essential amino acid. It is used as a cell culture media component and raw material in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Cystine dihydrochloride is a modified version of L-Cystine with improved solubility.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
L-Cystine is a natural proteinogenic amino acid sulfide dimer of L-cysteine. L-cystine is used as a cell culture supplement. L-cystine is also used to characterize and identify specific amino acid transport systems in cells such as system system Xc(─) .
in vivo
L-Cystine dihydrochloride (280 mg/kg, p.o., 11 days) administrated with L-theanine (HY-15121) enhances antigen-specific IgG production partly through augmentation of glutathione (GSH) levels and T helper 2 (Th2)-mediated responses in mice[2]. L-Cystine dihydrochloride (200 mg/kg, p.o., 11 days) administrated with L-theanine (HY-15121) (80 mg/kg, p.o., 11 days) significantly decreases the serum IL-10/IFN-γ ratio 6 hours after DNP-KLH antigenic stimulation, but increases the serum IL-10/IFN-γ ratio 24 hours after DNP-KLH antigenic stimulation in mice[2].
| Animal Model: | Nine-week-old female BALB/c mice[2] |
| Dosage: | 140, 280 and 560 mg/kg |
| Administration: | p.o. administration for 11 days |
| Result: | Increased IgG and IgM antibody production administrated with L-theanine (HY-15121) after DNP-dextran and DNP-KLH antigenic stimulation in mice. |
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L-CYSTINE DIHYDROCHLORIDE(30925-07-6)Related Product Information
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- 3,3'-Dithiodipropionic acid
- L-Cystine hydrochloride
- 3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID
- DL-Cystine
- L-Cystine
- L-Cysteine monohydrochloride
- DL-CYSTEINE HYDROCHLORIDE MONOHYDRATE
- DL-Cysteine hydrochloride
- Dimethyl L-cystinate dihydrochloride
- Cystamine dihydrochloride
- diethyl L-cystinate dihydrochloride
- L-Cystine bis(t-butyl ester) dihydrochloride
- DL-CYSTINE HYDROCHLORIDE
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