ChemicalBook > Product Catalog > Biochemical Engineering > Plant extracts > APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE
APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE
APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE Basic information
- Product Name:
- APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE
- Synonyms:
-
- 6-C-alpha-L-Arabinosyl-8-C-beta-D-glucosylapigenin
- Apigenin 6-C-alpha-L-arabinopyranoside-8-C-beta-D-glucopyranoside
- Isoshaftoside
- apigenin-6-α-L-arabinosyl-8-β-glucoside
- 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-6-[(2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]-4H-chromen-4-one (non-preferred name)
- 5,7-dihydroxy-2-(4-hydroR)-3,4,5-trihydroxy-6-(hydroxR,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]-4H-chromen-4-one (non-preferred name)
- 4H-1-Benzopyran-4-one, 6-α-L-arabinopyranosyl-8-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-
- 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-...
- CAS:
- 52012-29-0
- MF:
- C26H28O14
- MW:
- 564.49
- EINECS:
- 218-362-5
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- Tri-substituted Flavones
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 52012-29-0.mol
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APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE Chemical Properties
- Boiling point:
- 935.0±65.0 °C(Predicted)
- Density
- 1.766
- solubility
- Soluble in ethanol and methanol;
- pka
- 5.70±0.40(Predicted)
- form
- powder
- color
- Orange
- Water Solubility
- sparingly soluble in water
- InChIKey
- NKVFUCSDZNNOHZ-JOAYLRBINA-N
- SMILES
- C1(C2=CC=C(O)C=C2)OC2=C(C(=C(OC3OC[C@@H](O)[C@@H](O)[C@@H]3O)C(=C2OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O)O)C(=O)C=1 |&1:17,19,21,28,31,33,35,r|
- LogP
- 0.040 (est)
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APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Stachys sieboldii, Stachys sieboldii, Stachys sieboldii, Stachys sieboldii, Stachys sieboldii, Stachys sieboldii, Stachys sieboldii.
Uses
food and beverages
Definition
ChEBI: A C-glycosyl compound that is apigenin substituted at positions 6 and 8 by alpha-L-arabinopyranosyl and beta-D-glucosyl residues respectively.
in vivo
Isoschaftoside (20 mg/kg; i.p.; daily for 4 weeks) reverses the nonalcoholic fatty liver disease (NAFLD) and reduces hepatic steatosis in mice[3].
| Animal Model: | C57 mice fed with a high-fat diet (HFD) (4 weeks; male; C57BL/6JGpt)[3] |
| Dosage: | 20 mg/kg |
| Administration: | Intraperitoneal injection (i.p.); daily for 4 weeks |
| Result: | Significantly reduced the body weight and body size of the high-fat diet mice compared with the model group. Reduced the visceral fat weight of high-fat diet mice. Significantly attenuated hepatic lipid accumulation induced by a high-fat diet and decreased the number of intracellular lipid droplets and hepatocyte balloons. Reversed the damage to liver function and the elevation of blood glucose caused by a high-fat diet. The expression level of p62 and LC3-II was significantly lower than that in the HFD group. |
APIGENIN-6-ARABINOSIDE-8-GLUCOSIDESupplier
Wuhan ChemFaces Biochemical Co., Ltd. Gold
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- 18607101326 15172504745
- aileen@chemfaces.com
Shanghai Pureone Bio Technology, CO. LTD Gold
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- 18302135232 18302135232
- pureonebio@163.com
Chembest Research Laboratories Limited
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- +86-21-20908456
- sales@BioChemBest.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
Chengdu Biopurify Phytochemicals Ltd.
- Tel
- +86-028-82633397 18982077548
- cwb1@biopurify.cn