(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Chemical Properties

Boiling point:

523.8±50.0 °C(Predicted)

Density 

1.273±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

10.62±0.20(Predicted)

form 

Solid

color 

Light Yellow

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Usage And Synthesis

Uses

(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity.

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester(1168150-46-6)Related Product Information

• Methyl 2-oxoindole-6-carboxylate
• 1-Chloro-4-(trimethoxymethyl)benzene
• Methyl 1-acetyl-2-oxoindoline-6-carboxylate
• N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
• N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
• BIBF 1202
• (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
• Avibactam sodium
• Nintedanib
• 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
• Avibactam INT 1
• BIBF-1120
• 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
• Nintedanib Ethanesulfonate Salt
• 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
• N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
• N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
• 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide