N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Chemical Properties

Melting point:

94 - 96°C

Boiling point:

446.9±40.0 °C(Predicted)

Density 

1.230

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

7.43±0.10(Predicted)

form 

Solid

color 

Pale Yellow to Light Yellow

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Usage And Synthesis

Uses

N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is used as a reactant in the synthetic preparation of 6-methoxycarbonyl-substituted indolinones, such as Intedanib (I666650), which is a triple angiokinase inhibitor and antitumor agent.

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide(1139453-98-7)Related Product Information

• 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID
• N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
• Methyl oxindole-5-carboxylate
• Nintedanib
• N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
• Methyl 1-acetyl-2-oxoindoline-6-carboxylate
• N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide
• 1-Chloro-4-(trimethoxymethyl)benzene
• 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
• BIBF 1202
• Nintedanib Ethanesulfonate Salt
• 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
• N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
• 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide
• 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
• BIBF-1120
• (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
• (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate