4-(Trifluoromethoxy)phenyl isocyanate Chemical Properties

Melting point:

-29°C

Boiling point:

78 °C (22 mmHg)

Density 

1.346 g/mL at 25 °C(lit.)

vapor pressure 

1.42hPa at 25℃

refractive index 

n20/D 1.458(lit.)

Flash point:

158 °F

storage temp. 

Refrigerator (+4°C)

form 

clear liquid

color 

Colorless to Light yellow

Water Solubility 

Reacts with water.

Sensitive 

Moisture Sensitive

BRN 

977669

LogP

2.12

CAS DataBase Reference

35037-73-1(CAS DataBase Reference)

EPA Substance Registry System

4-(Trifluoromethoxy)phenyl isocyanate (35037-73-1)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38-42

Safety Statements 

26-36-36/37-22

RIDADR 

UN 2206 6.1/PG 3

WGK Germany 

3

F 

21

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29291090

MSDS

• Language:English Provider:4-(Trifluoromethoxy)phenyl isocyanate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-(Trifluoromethoxy)phenyl isocyanate Usage And Synthesis

Chemical Properties

clear colorless to slightly yellow liquid

Uses

4-(Trifluoromethoxy)phenyl Isocyanate is a reactant in the synthesis of 4-aryl-7-hydroxyindoline-based P2Y1 antagonists as novel antiplatelet agents.

4-(Trifluoromethoxy)phenyl isocyanate(35037-73-1)Related Product Information

• 4-Methoxybenzoic acid
• (Trifluoromethoxy)benzene
• 2-(Trifluoromethoxy)aniline
• p-Trifluoromethoxy phenol
• 4-Methoxyphenylacetic acid
• m-Anisyl alcohol
• Anisole
• Isocyanatocyclohexane
• 4-(Trifluoromethoxy)chlorobenzene
• 4-(Trifluoromethoxy)aniline
• 4-(Trifluoromethoxy)benzaldehyde
• Propyl isocyanate
• 4-Methoxyphenylacetone
• 4'-(Trifluoromethoxy)acetophenone
• 4-Methoxybenzyl cyanide
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• p-Anisaldehyde
• 3-(Trifluoromethoxy)aniline