N-Phenylbenzylamine Chemical Properties

Melting point:

35-38 °C (lit.)

Boiling point:

306-307 °C (lit.)

Density 

1.061 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5325(lit.)

Flash point:

217 °F

storage temp. 

Store below +30°C.

solubility 

alcohol: soluble

form 

Crystalline Powder or Low Melting Mass

pka

3.89±0.10(Predicted)

Specific Gravity

1.061

color 

Colorless to yellow-beige

Water Solubility 

INSOLUBLE

Merck 

14,1126

CAS DataBase Reference

103-32-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzenemethanamine, N-phenyl-(103-32-2)

EPA Substance Registry System

Benzenemethanamine, N-phenyl- (103-32-2)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

RIDADR 

UN 2577 8/PG 2

WGK Germany 

3

F 

21

HS Code 

29214980

MSDS

• Language:English Provider:Benzylaniline
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

N-Phenylbenzylamine Usage And Synthesis

Synthesis

N-Phenylbenzylamine can be obtained by condensation of benzyl chloride and aniline. Mix and stir sodium bicarbonate, water and aniline, heat to 90-95°C, and slowly add benzyl chloride. React at 90-95°C for 3h. Cool and filter. The filtrate was separated, and the organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. Then, under reduced pressure distillation, the 81°C (1.6kPa) fraction was collected to recover aniline, and the 170-190°C (1.6kPa) fraction was cooled and solidified to give N-Phenylbenzylamine.

Chemical Properties

colorless to yellow-beige crystalline powder

Uses

N-Benzylaniline is a major metabolite of the antihistaminic Antazoline and other N-substituted benzylanilines.

Uses

N-Benzylaniline was used in the separation of tervalent gallium, indium and thallium by solvent extraction method.

Synthesis Reference(s)

Chemistry Letters, 8, p. 45, 1979
Organic Syntheses, Coll. Vol. 1, p. 102, 1941
Tetrahedron Letters, 19, p. 4987, 1978 DOI: 10.1016/S0040-4039(01)85789-0

General Description

The electropolymerisation of N-benzylaniline at transparent Indium Tin Oxide glass electrodes has been investigated by UV-visible spectroelectrochemistry. N-Benzylaniline on electrochemical oxidation in aqueous sulfuric acid solution produces an adherent conducting polymer film at the platinum electrode.

Purification Methods

Crystallise the amine from pet ether (b 60-80o) (ca 0.5mL/g). The picrate has m 113o (from Et2O). [Beilstein 12 H 1023, 12 I 449, 12 II 548, 12 III 2215, 12 IV 2172.]

N-Phenylbenzylamine(103-32-2)Related Product Information

• Benzyl bromide
• Benzalacetone
• Benzyltrimethylammonium chloride
• Benzyltriethylammonium chloride
• Benzyl chloride
• N,N-Dimethylbenzylamine
• DIBENZYLTOLUENE
• Phthalylsulfathiazole
• Salicylanilide
• N-Phenylbenzohydroxamic acid
• CHLORANTINE FAST RED 5B
• 5-CHLOROSALICYLANILIDE
• XYLIDYL BLUE I SODIUM SALT
• BENZANILIDE
• N-ETHYL-N-PHENYLBENZYLAMINE
• NAPHTHOL AS-BI PHOSPHATE
• Fast Blue BB
• CI 37155