3-Oxocyclobutanecarboxylic acid

Product Name: 3-Oxocyclobutanecarboxylic acid
CAS No.: 23761-23-1
Chemical Name: 3-Oxocyclobutanecarboxylic acid
Synonyms: 3-oxocyclobutane-1-carboxylic acid;3-OXO-CYCLOBUTANECARBOXYLIC ACID;3-oxocyclobutane-1,1-dicarboxylic acid;3-OxocycL;IFLAB-BB F2124-0041;1-Carboxy-3-oxocyclobutane;3-Oxocyclobutanecarboxylic;3-Oxocyclobutanecarboxyli...;Oxocyclobutanecarboxylic acid;3-Oxycyclobutanecarboxylic acid
CBNumber: CB0111483
Molecular Formula: C5H6O3
Formula Weight: 114.1
MOL File: 23761-23-1.mol

More

Less

3-Oxocyclobutanecarboxylic acid Property

Melting point:: 69-70℃
Boiling point:: 296°C
Density: 1.431
Flash point:: 147°C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Solid
pka: 4.35±0.20(Predicted)
color: Off-white
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C5H6O3/c6-4-1-3(2-4)5(7)8/h3H,1-2H2,(H,7,8)
InChIKey: IENOFRJPUPTEMI-UHFFFAOYSA-N
SMILES: C1(C(O)=O)CC(=O)C1
CAS DataBase Reference: 23761-23-1(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 26-37-60
TSCA: No
HS Code: 29189900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS004694
Product name: 3-Oxocyclobutanecarboxylic acid
Purity: AldrichCPR
Packaging: 100mg
Price: $70.9
Updated: 2024/03/01

TCI Chemical

Product number: O0392
Product name: 3-Oxocyclobutanecarboxylic Acid
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: O0392
Product name: 3-Oxocyclobutanecarboxylic Acid
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $52
Updated: 2024/03/01

Alfa Aesar

Product number: H64774
Product name: 3-Oxocyclobutanecarboxylic acid, 98%
Packaging: 5g
Price: $51.65
Updated: 2024/03/01

Alfa Aesar

Product number: H64774
Product name: 3-Oxocyclobutanecarboxylic acid, 98%
Packaging: 25g
Price: $207.65
Updated: 2024/03/01

More

Less

3-Oxocyclobutanecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

3-Oxocyclobutanecarboxylic Acid (cas# 23761-23-1) is a compound useful in organic synthesis.

Application

3-Oxocyclobutanecarboxylic acid is a very important medicine intermediate, it is widely applied in the synthetic of tens kinds of bulk drugs, such as ACK1 antibody, the MDM2 antagonist, the JAK inhibitor, CETP inhibitor, kinase inhibitor, the PDE10 inhibitor, thrombin inhibitors and in autoimmunization chronic inflammatory diseases and antitumor drug, all being used to.

Preparation

The target product 3-oxocyclobutanecarboxylic acid is obtained by adopting acetone, bromine, and malononitrile as raw materials, adopting ethanol, DMF (dimethyl formamide), and water as solvents, adopting sodium iodide as an activating agent and tetrabutylammonium bromide (TBAB) as a phase transfer catalyst through three-step reaction.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 3841, 1988 DOI: 10.1021/jo00251a033

3-Oxocyclobutanecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Oxocyclobutanecarboxylic acid Suppliers

Americas 1 Canada 3 China 412 Europe 1 Germany 2 India 35 Japan 1 Switzerland 2 Ukraine 2 United Kingdom 6 United States 35 Global 500

BTC Pharmaceutical CO. Ltd

Tel: 0513-0513-68015-397-397 15716293042
Fax: 0513-68015394
Email: sales14@btcpharm.com
Country: China
ProdList: 648
Advantage: 55

Mashilabs (Shanghai) Co.,Ltd.

Tel: 021-00000000 19916721580
Fax: QQ：3154870176
Email: info@mashilabs.com
Country: China
ProdList: 4115
Advantage: 58

Chongqing Acemol Technology Co.,Ltd

Tel: 023-86822659 18611316925
Email: sales@acemol.com
Country: China
ProdList: 952
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16687
Advantage: 50

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: 495745175@qq.com
Country: China
ProdList: 6864
Advantage: 58

Z IntellecChem& Tech. Co., Ltd

Tel: 15050866711
Fax: QQ:2677337387
Email: saleszchem@163.com
Country: China
ProdList: 104
Advantage: 62

Wuhan Luyi New Material Co., Ltd.

Tel: 027-81360608 13971310049
Fax: 027-81360608
Email: 109321999@qq.com
Country: China
ProdList: 52
Advantage: 58

Nanjing Vcare PharmaTech Co., Ltd

Tel: 025-58741518 17366379912
Email: sales@vcarepharmatech.com
Country: China
ProdList: 463
Advantage: 58

Beijing Whale Technology Corporation Ltd.

Tel: 010-83694934 13671295325
Email: sales@whalecorporation.com
Country: China
ProdList: 126
Advantage: 58

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

More

Less

View Lastest Price from 3-Oxocyclobutanecarboxylic acid manufacturers

Hebei Dangtong Import and export Co LTD

Product: 3-Oxocyclobutanecarboxylic acid 23761-23-1
Price: US $874.00-862.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-03-02

Henan Fengda Chemical Co., Ltd

Product: 3-Oxocyclobutanecarboxylic acid 23761-23-1
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-15

Shaanxi Haibo Biotechnology Co., Ltd

Product: 3-Oxocyclobutanecarboxylic acid 23761-23-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-31

23761-23-1, 3-Oxocyclobutanecarboxylic acidRelated Search:

1-DODECANESULFONIC ACID SODIUM SALT TRIMETHYLENE OXIDE 1-Bromobutane Sodium dodecyl sulfate Cyclopropane 1-Hexadecylpyridinium bromide 2-Bromo-2-methylpropane 1-Chloro-2-methylpropane Folic acid Oxygen-fluorine acid Stearic acid Ethyl 2-(Chlorosulfonyl)acetate Levofloxacin carboxylic acid 2-Chloro-2-methylpropane Citric acid Ascoric Acid Cyclobutanecarboxylic acid Cyclobutanemethanol

3-OXO-CYCLOBUTANECARBOXYLIC ACID

(3-oxocyclobutyl)carboxylic acid

3-Oxycyclobutanecarboxylic acid

3-Oxo-cyclobutanecarboxylic acid ,95%

3-Oxocyclobutanecarboxyli...

3-oxocyclobutanecarboxylic acid(SALTDATA: FREE)

3-Oxocyclobutane-1-carboxylic acid 98%

IFLAB-BB F2124-0041

CYCLOBUTANECARBOXYLIC ACID, 3-OXO-

3-Oxocyclobutanecarboxylic

1-Carboxy-3-oxocyclobutane

3-oxocyclobutane-1-carboxylic acid

3-Oxocyclobutanecarboxylic acid 98%

3-oxocyclobutane-1,1-dicarboxylic acid

3-Oxo-1-cyclobutanecarboxylic Acid

3-Oxocyclobutanecarboxylic Acid, 97+%

cyclobutanone-3-carboxylic acid

3-OxocyclobutanecarboxylicAcid&gt

3-OxocycL

3-oxo-cyclobutylkylcarboxylic acid

CAS 23761-23-1 3-Oxocyclobutanecarboxylic acid

Oxocyclobutanecarboxylic acid

3-Oxocyclobutanyl carboxylic acid

23761-23-1

Building Blocks/Intermediates

API intermediates

Pharmaceutical intermediate

Miscellaneous Reagents