ChemicalBook > CAS DataBase List > (S)-(-)-2-Azetidinecarboxylic acid
(S)-(-)-2-Azetidinecarboxylic acid
- Product Name
- (S)-(-)-2-Azetidinecarboxylic acid
- CAS No.
- 2133-34-8
- Chemical Name
- (S)-(-)-2-Azetidinecarboxylic acid
- Synonyms
- (S)-AZETIDINE-2-CARBOXYLIC ACID;H-AZE-OH;L-AZETIDINE-2-CARBOXYLIC ACID;L-H-Aze-OH;H-AZE(2)-OH;(S)-(-)-2-Azetidinec;N,3-Methylene-L-alanine;L-AZETIDINECARBOXYLIC ACID;l-2-azetidinecarboxylicaci;azetidyl-2-carboxylic acid
- CBNumber
- CB0128117
- Molecular Formula
- C4H7NO2
- Formula Weight
- 101.1
- MOL File
- 2133-34-8.mol
More
Less
(S)-(-)-2-Azetidinecarboxylic acid Property
- Melting point:
- ~215 °C (dec.)
- alpha
- -125 º (c=1, water 25 ºC)
- Boiling point:
- 189.47°C (rough estimate)
- Density
- 1.2245 (rough estimate)
- refractive index
- -122 ° (C=4, H2O)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 2.35±0.20(Predicted)
- form
- Crystalline Powder or Crystals
- color
- White to light beige
- Water Solubility
- 5 g/100 mL
- Merck
- 14,908
- BRN
- 80678
- InChIKey
- IADUEWIQBXOCDZ-VKHMYHEASA-N
- CAS DataBase Reference
- 2133-34-8(CAS DataBase Reference)
More
Less
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- RTECS
- CM4310500
- Hazard Note
- Irritant
- HS Code
- 29339900
- Hazardous Substances Data
- 2133-34-8(Hazardous Substances Data)
- Toxicity
- LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A0760
- Product name
- L-Azetidine-2-carboxylic acid
- Purity
- ≥99%
- Packaging
- 50mg
- Price
- $85.9
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- A0760
- Product name
- L-Azetidine-2-carboxylic acid
- Purity
- ≥99%
- Packaging
- 1g
- Price
- $711
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A1043
- Product name
- L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $279
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A1043
- Product name
- L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
- Purity
- >98.0%(T)
- Packaging
- 100mg
- Price
- $49
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L09668
- Product name
- (S)-(-)-Azetidine-2-carboxylic acid, 98%
- Packaging
- 250mg
- Price
- $120.65
- Updated
- 2024/03/01
More
Less
(S)-(-)-2-Azetidinecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.
Uses
L-Azetidine-2-carboxylic acid has been used as a:
- collagen synthesis inhibitor
- protein folding antagonist
- as a standard in liquid chromatography-mass spectrometry
Uses
(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.
Definition
ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.
General Description
L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.
Biochem/physiol Actions
Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
Safety Profile
Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.
(S)-(-)-2-Azetidinecarboxylic acid Preparation Products And Raw materials
Raw materials
Potassium tert-butoxide
Acetonitrile
2-Bromoethanol
Potassium carbonate
Palladium
L-1-Phenylethylamine
Tetrahydrofuran
Diethyl ether
Ammonium chloride
Ethyl acetate
Hydrochloric acid
Bromoacetonitrile
Sodium bicarbonate
Dichloromethane
Methanol
Dimethyl sulfoxide
Thionyl chloride
PETROLEUM ETHER
Preparation Products
More
Less
(S)-(-)-2-Azetidinecarboxylic acid Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
More
Less
View Lastest Price from (S)-(-)-2-Azetidinecarboxylic acid manufacturers
Honest Joy Holdings Limited
- Product
- (S)-L-Azetidine-2-carboxylic acid 2133-34-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- (S)-(-)-2-Azetidinecarboxylic acid 2133-34-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] 2133-34-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
2133-34-8, (S)-(-)-2-Azetidinecarboxylic acidRelated Search:
Citric acid
Calconcarboxylic acid
Albuterol sulfate
2,5-PYRIDINEDICARBOXYLIC ACID
Cyclobutylamine
DOBUTAMINE
ISOBUTANE
TRIMETHYLENE OXIDE
AMIKACIN
Quinolinic acid
Azetidine
n-Butane
Salbutamol
1-Chloro-2-methylpropane
3-Azetidinecarboxylic acid
Ascoric Acid
(S)-BENZYL 2-AZETIDINONE-4-CARBOXYLATE
1-Boc-L-azetidine-2-carboxylic acid