(S)-(-)-2-Azetidinecarboxylic acid

Product Name: (S)-(-)-2-Azetidinecarboxylic acid
CAS No.: 2133-34-8
Chemical Name: (S)-(-)-2-Azetidinecarboxylic acid
Synonyms: (S)-AZETIDINE-2-CARBOXYLIC ACID;H-AZE-OH;L-AZETIDINE-2-CARBOXYLIC ACID;L-H-Aze-OH;H-AZE(2)-OH;(S)-(-)-2-Azetidinec;N,3-Methylene-L-alanine;L-AZETIDINECARBOXYLIC ACID;l-2-azetidinecarboxylicaci;azetidyl-2-carboxylic acid
CBNumber: CB0128117
Molecular Formula: C4H7NO2
Formula Weight: 101.1
MOL File: 2133-34-8.mol

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(S)-(-)-2-Azetidinecarboxylic acid Property

Melting point:: ~215 °C (dec.)
alpha: -125 º (c=1, water 25 ºC)
Boiling point:: 189.47°C (rough estimate)
Density: 1.2245 (rough estimate)
refractive index: -122 ° (C=4, H2O)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
pka: 2.35±0.20(Predicted)
form: Crystalline Powder or Crystals
color: White to light beige
Water Solubility: 5 g/100 mL
Merck: 14,908
BRN: 80678
InChIKey: IADUEWIQBXOCDZ-VKHMYHEASA-N
CAS DataBase Reference: 2133-34-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
RTECS: CM4310500
Hazard Note: Irritant
HS Code: 29339900
Hazardous Substances Data: 2133-34-8(Hazardous Substances Data)
Toxicity: LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A0760
Product name: L-Azetidine-2-carboxylic acid
Purity: ≥99%
Packaging: 50mg
Price: $85.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: A0760
Product name: L-Azetidine-2-carboxylic acid
Purity: ≥99%
Packaging: 1g
Price: $711
Updated: 2024/03/01

TCI Chemical

Product number: A1043
Product name: L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
Purity: >98.0%(T)
Packaging: 1g
Price: $279
Updated: 2024/03/01

TCI Chemical

Product number: A1043
Product name: L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
Purity: >98.0%(T)
Packaging: 100mg
Price: $49
Updated: 2024/03/01

Alfa Aesar

Product number: L09668
Product name: (S)-(-)-Azetidine-2-carboxylic acid, 98%
Packaging: 250mg
Price: $120.65
Updated: 2024/03/01

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(S)-(-)-2-Azetidinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.

Uses

L-Azetidine-2-carboxylic acid has been used as a:

collagen synthesis inhibitor
protein folding antagonist
as a standard in liquid chromatography-mass spectrometry

Uses

(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.

Definition

ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.

General Description

L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.

Biochem/physiol Actions

Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.

Safety Profile

Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.

(S)-(-)-2-Azetidinecarboxylic acid Preparation Products And Raw materials

Raw materials

Potassium tert-butoxide Acetonitrile 2-Bromoethanol Potassium carbonate Palladium L-1-Phenylethylamine Tetrahydrofuran Diethyl ether Ammonium chloride Ethyl acetate Hydrochloric acid Bromoacetonitrile Sodium bicarbonate Dichloromethane Methanol Dimethyl sulfoxide Thionyl chloride PETROLEUM ETHER

Preparation Products

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(S)-(-)-2-Azetidinecarboxylic acid Suppliers

Americas 1 Belgium 1 Canada 1 China 222 Europe 3 Germany 3 India 9 Japan 8 Slovakia 1 South Korea 1 Sweden 2 Switzerland 7 The Netherlands 1 United Kingdom 19 United States 54 USA 1 Global 334

Christof Senn Laboratories AG

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Fischer Chemicals AG

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Matrix Fine Chemicals GmbH

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Bachem AG

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SIGMA-RBI

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Senn Chemicals AG

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Lipomed AG

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View Lastest Price from (S)-(-)-2-Azetidinecarboxylic acid manufacturers

Honest Joy Holdings Limited

Product: (S)-L-Azetidine-2-carboxylic acid 2133-34-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 100 tons
Release date: 2022-01-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: (S)-(-)-2-Azetidinecarboxylic acid 2133-34-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] 2133-34-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

2133-34-8, (S)-(-)-2-Azetidinecarboxylic acidRelated Search:

Citric acid Calconcarboxylic acid Albuterol sulfate 2,5-PYRIDINEDICARBOXYLIC ACID Cyclobutylamine DOBUTAMINE ISOBUTANE TRIMETHYLENE OXIDE AMIKACIN Quinolinic acid Azetidine n-Butane Salbutamol 1-Chloro-2-methylpropane 3-Azetidinecarboxylic acid Ascoric Acid (S)-BENZYL 2-AZETIDINONE-4-CARBOXYLATE 1-Boc-L-azetidine-2-carboxylic acid

(S)-(-)-2-AZETIDINECARBOXYLIC ACID

(S)-2-AZETIDINE CARBOXYLIC ACID

(S)-(-)-AZETIDINE-2-CARBOXYLIC ACID

(S)-AZETIDINE-2-CARBOXYLIC ACID

(S)-L-2-AZETIDINE CARBOXYLIC ACID

(2S)-(-)-AZETIDINE-2-CARBOXYLIC ACID

L-TRIMETHYLENEIMINE-2-CARBOXYLIC ACID

L-AZETIDINE-2-CARBOXYLIC ACID

L-AZETIDINECARBOXYLIC ACID

L-2-AZETIDINECARBOXYLIC ACID

H-AZE(2)-OH

H-AZE-OH

(S)-Azetidine-2-carboxylic acid, L-2-Azetidinecarboxylic acid, L-Azetidine-2-carboxylic acid

(2S)-2-Azetidinecarboxylic acid

N,3-Methylene-L-alanine

(s)-2-azetidinecarboxylicaci

2-Azetidinecarboxylic acid, (2S)-

L-Azetidine-2-carboxylic acid ,98%

L-Azetidine-2-carboxylic acid ,99%

(S)-(-)-2-Azetidinec

(S)-(-) Azetidine-2-carbo...

(S)-L-Azetidine-2-carboxylic acid

(S) - (-) - 2- carboxy cyclobutylaMine

(S)-2-Azetidine-2-carboxylic acid

L-Azetidine-2-carboxylic acid≥ 97% (Assay)

acidel-azetidine-2-carboxylic

acidel-azetidine-2-carboxylic(french)

l-2-azetidinecarboxylicaci

l-azetidine-2-carboxylicaci

L-AZETIDINE-2-CARBOXYLIC ACID*CRYSTALLIN E

(S)-(-)-2-AZETIDINECARBOXYLIC ACID, 99+%

(S)-(-)-2-Azetidinecarboxylic

azetidyl-2-carboxylic acid

L-H-Aze-OH

L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]

L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]&gt

(S)-(-)-2-Azetidinecarboxylic acid ISO 9001：2015 REACH

(S)-Azetidine-2-carboxylic acid/(S)-2-Azetidine carboxylic acid/L-Azetidine-2-carboxylic acid

(S)-azetidine-2-carboxylicaci

(-)-Azetidinecarboxylic acid

(S)-Azetidine carboxylic acid

2133-34-8

Chiral Building Blocks

Carboxylic Acids (Chiral)

Simple 4-Membered Ring Compounds

Azetidines

Cell Biology

Angiogenesis Regulators

BioChemical

Cell Signaling and Neuroscience

Extracellular Matrix

Cytoskeleton and Extracellular Matrix

Others

Peptide Synthesis

Unnatural Amino Acid Derivatives

Specialty Synthesis

Amino Acids 13C, 2H, 15N

Carboxylic Acids (Chiral)