L-Lactic dehydrogenase
- Product Name
- L-Lactic dehydrogenase
- CAS No.
- 9001-60-9
- Chemical Name
- L-Lactic dehydrogenase
- Synonyms
- LD;LAD;LDH;MFH1;MFI7;L-LDH;FOXC2;MFH-1;LCAMB;FKHL14
- CBNumber
- CB0304186
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
L-Lactic dehydrogenase Property
- storage temp.
- 2-8°C
- solubility
- aqueous buffer: soluble
- form
- suspension
- color
- white
- PH
- 7.5
- biological source
- rabbit muscle
- Water Solubility
- low ionic strength buffer: soluble
water: soluble - Merck
- 13,5349
- Specific Activity
- 800-1,200units/mg protein
- CAS DataBase Reference
- 9001-60-9
- EPA Substance Registry System
- Dehydrogenase, lactate (9001-60-9)
Safety
- Risk Statements
- 21/22-36/37/38
- Safety Statements
- 22-24/25-36/37-26
- WGK Germany
- 3
- F
- 3-10
- HS Code
- 35079090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- SAB1412479
- Product name
- ANTI-FOXC2 antibody produced in mouse
- Purity
- clone 1D4, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- SAB1412346
- Product name
- ANTI-FOXC2 antibody produced in mouse
- Purity
- clone 4A3, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μG
- Price
- $541
- Updated
- 2025/07/31
- Product number
- SAB1412345
- Product name
- ANTI-FOXC2 antibody produced in mouse
- Purity
- clone 4A5, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- SAB1412344
- Product name
- ANTI-FOXC2 antibody produced in mouse
- Purity
- clone 3E6, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- SAB1412343
- Product name
- ANTI-FOXC2 antibody produced in mouse
- Purity
- clone 3H5, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
L-Lactic dehydrogenase Chemical Properties,Usage,Production
Chemical Properties
Off-white lyophilized powder or crystalline suspension of 3.2 mol/L ammonium sulfate, soluble in water, pI of 4.6, optimum pH 6.0.Stability: crystalline enzyme solution can be stored for 6-8 weeks with unchanged activity, sulfate suspension can be stabilized for more than a year, very dilute solution is unstable; optimum temperature of 39 ℃, rapid inactivation of temperatures above 60 ℃. Inhibitors are excess pyruvate, excess NAD, oxalic acid, oxalic acid monoamide, hydroxymalonic acid, malonic acid, urea, Cu2+, Hg2+, Ag+, 4-chloromercuric benzoic acid, pyrophosphoric acid or phosphate buffer and non-competitive inhibitors formed from coenzyme I (NAD) in alkaline inhibit oxidation reaction, excess lactate and non-competitive inhibitors formed from reduced coenzyme I (NADH) inhibit reduction reaction. inhibitors inhibit the reduction reaction; activators are 2-amino-2-methyl-1-propanol, fluoride, diethanolamine, and heparin (oxidizing). Enzymatic reaction: pyruvate + reduced coenzyme I + H+ ═ lactate + coenzyme I.
Uses
L-Lactic Dehydrogenase from bovine heart has been used in ATPase assay of R2 complex Rvb1p-Rvb2p, RecA protein and sarcoplasmic reticulum Ca2+-ATPase (SERCA).
Uses
L-Lactic dehydrogenase is used in the determination of pyruvate (used in conjunction with reduced coenzyme) and in the diagnosis of myocardial infarction and leukemia.
Uses
L-Lactic Dehydrogenase from bovine heart has been used as a standard in cytotoxicity assay. It has also been used in glutamic pyruvic transaminase (GPT) assay.
General Description
L-lactate dehydrogenase (LDH) is an enzyme that catalyzes the conversion of lactate to pyruvate.?In particular, lactic dehydrogenase A (LDHA) is mainly found in skeletal muscle, and for that reason is known as the M subunit. This recombinant form of LDHA has a C-terminal histidine-tag.
The gene LDHA (L-lactate dehydrogenase A chain) is mapped to human chromosome 11p15. It is a subunit of lactate dehydrogenase.
Biochem/physiol Actions
Also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids.
Purification Methods
A forty-fold purification of the dehydrogenase is effected by affinity chromatography using Sepharose 4B coupled to 8-(6-aminohexyl)amino-5'-AMP or -NAD . [Lees et al. Arch Biochem Biophys 163 561 1974, Pesce et al. J Biol Chem 239 1753 1964.]
L-Lactic dehydrogenase Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-Lactic dehydrogenase manufacturers
- Product
- L-Lactic dehydrogenase 9001-60-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98.0%
- Supply Ability
- 1kg/month
- Release date
- 2021-08-27
- Product
- LACTATE DEHYDROGENASE 9001-60-9
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-09-09
- Product
- L-Lactic dehydrogenase 9001-60-9
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2024-08-30