t-Boc-N-amido-PEG1-acid
- Product Name
- t-Boc-N-amido-PEG1-acid
- CAS No.
- 1260092-44-1
- Chemical Name
- t-Boc-N-amido-PEG1-acid
- Synonyms
- 3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid;Boc-NH-PEG1-COOH;NH-PEG1-CH2CH2COOH;Boc-PEG1-CH2CH2COOH;Boc-N-amido-PEG1-acid;Boc-NH-PEG1-CH2CH2COOH;t-Boc-N-amido-PEG1-acid;t-Boc-N-amido-PEG1-CH2COOH;t-Boc-N-amido-PEG1-acid t-Boc;t-boc-N-amido-PEG1-propionic acid
- CBNumber
- CB03062663
- Molecular Formula
- C10H19NO5
- Formula Weight
- 233.26
- MOL File
- 1260092-44-1.mol
t-Boc-N-amido-PEG1-acid Property
- Boiling point:
- 385.0±27.0 °C(Predicted)
- Density
- 1.127±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.29±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B671343
- Product name
- Boc-NH-PEG1-CH2CH2COOH
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-20910
- Product name
- t-Boc-N-amido-PEG1-acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- BIPG1799
- Product name
- t-Boc-N-amido-PEG1-acid
- Packaging
- 500mg
- Price
- $410
- Updated
- 2021/12/16
- Product number
- 0262DB
- Product name
- 3-(2-((Tert-butoxycarbonyl)amino)ethoxy)propanoicacid
- Packaging
- 5g
- Price
- $531
- Updated
- 2021/12/16
- Product number
- BP-20910
- Product name
- t-Boc-N-amido-PEG1-acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $625
- Updated
- 2021/12/16
t-Boc-N-amido-PEG1-acid Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG1-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Biological Activity
Boc-NH-PEG1-CH2CH2COOH is a cleavable ADC linker containing 1 unit PEG, and also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used for the synthesis of antibody-drug conjugates (ADC) and PROTACs .
target
PEGs
| Alkyl/ether
| Cleavable
|
t-Boc-N-amido-PEG1-acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from t-Boc-N-amido-PEG1-acid manufacturers
- Product
- t-Boc-N-amido-PEG1-acid 1260092-44-1
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25