t-Boc-N-amido-PEG1-acid

Product Name: t-Boc-N-amido-PEG1-acid
CAS No.: 1260092-44-1
Chemical Name: t-Boc-N-amido-PEG1-acid
Synonyms: 3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid;Boc-NH-PEG1-COOH;NH-PEG1-CH2CH2COOH;Boc-PEG1-CH2CH2COOH;Boc-N-amido-PEG1-acid;Boc-NH-PEG1-CH2CH2COOH;t-Boc-N-amido-PEG1-acid;t-Boc-N-amido-PEG1-CH2COOH;t-Boc-N-amido-PEG1-acid t-Boc;t-boc-N-amido-PEG1-propionic acid
CBNumber: CB03062663
Molecular Formula: C10H19NO5
Formula Weight: 233.26
MOL File: 1260092-44-1.mol

More

Less

t-Boc-N-amido-PEG1-acid Property

Boiling point:: 385.0±27.0 °C(Predicted)
Density: 1.127±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.29±0.10(Predicted)
form: Solid
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B6257
Product name: 3-[2-[(tert-Butoxycarbonyl)amino]ethoxy]propanoic Acid
Purity: min. 93.0 %
Packaging: 250MG
Price: $115
Updated: 2025/07/31

TRC

Product number: B671343
Product name: Boc-NH-PEG1-CH2CH2COOH
Packaging: 10mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-20910
Product name: t-Boc-N-amido-PEG1-acid
Purity: 98%
Packaging: 1g
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: 0262DB
Product name: 3-(2-((Tert-butoxycarbonyl)amino)ethoxy)propanoicacid
Packaging: 5g
Price: $531
Updated: 2021/12/16

BroadPharm

Product number: BP-20910
Product name: t-Boc-N-amido-PEG1-acid
Purity: 98%
Packaging: 5G
Price: $625
Updated: 2021/12/16

More

Less

t-Boc-N-amido-PEG1-acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG1-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs[1][2].

Biological Activity

Boc-NH-PEG1-CH2CH2COOH is a cleavable ADC linker containing 1 unit PEG, and also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used for the synthesis of antibody-drug conjugates (ADC) and PROTACs .

target

PEGs

Alkyl/ether

Cleavable

IC 50

PEGs; Alkyl/ether; Cleavable Linker

References

[1] Alex Cortez, et al.Antibody conjugates comprising toll-like receptor agonist and combination therapies. WO2018198091A1.
[2] Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

t-Boc-N-amido-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

t-Boc-N-amido-PEG1-acid Suppliers

China 105 India 3 United Kingdom 1 United States 8 Global 117

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

More

Less

View Lastest Price from t-Boc-N-amido-PEG1-acid manufacturers

LAURENT

Product: BocNH-PEG1-CH2CH2COOH 1260092-44-1
Price: US $32.25/g
Min. Order: 10g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-22

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoic acid 1260092-44-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: t-Boc-N-amido-PEG1-acid 1260092-44-1
Price: US $0.00/g
Min. Order: 25g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-25

1260092-44-1, t-Boc-N-amido-PEG1-acidRelated Search:

Ethylene glycol diacetate Azido-PEG4-NHBoc O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]polyethylene glycol 3000 t-Boc-N-amido-PEG2-NHS ester t-Boc-N-Amido-PEG2-Propargyl O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate t-boc-N-amido-PEG4-NHS ester Z-8-aMino-3,6-dioxaoctanoic acid t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG2-acid 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID t-Boc-Aminoxy-PEG3-Azide t-Boc-N-Amido-PEG4-Azide t-Boc-Aminoxy-PEG4-alcohol

t-Boc-N-amido-PEG1-acid

Boc-N-amido-PEG1-acid

t-boc-N-amido-PEG1-propionic acid

Boc-NH-PEG1-CH2CH2COOH

3-[2-(Boc-amino)ethoxy]propanoic acid

3-(2-T-BOC-AMINOETHOXY)PROPANOIC ACID

Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-

3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid

Boc-NH-PEG1-COOH

t-Boc-N-amido-PEG1-CH2COOH

3-[2-(tert-Butoxycarbonylamino)ethoxy]propionic acid

Boc-PEG1-CH2CH2COOH

t-Boc-N-amido-PEG1-acid t-Boc

NH-PEG1-CH2CH2COOH

3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid

3-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]propanoic acid

1260092-44-1

peg