BMS-986205
- Product Name
- BMS-986205
- CAS No.
- 1923833-60-6
- Chemical Name
- BMS-986205
- Synonyms
- Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;BMS-986205(Linrodostat);Linrodostat(BMS-986205);LINRODOSTAT;BMS 986205;BMS986205;(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
- CBNumber
- CB03339862
- Molecular Formula
- C24H24ClFN2O
- Formula Weight
- 410.91
- MOL File
- 1923833-60-6.mol
BMS-986205 Property
- Boiling point:
- 606.8±45.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:42.0(Max Conc. mg/mL);73.75(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);175.59(Max Conc. mM) - pka
- 13.80±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B596415
- Product name
- BMS-986205
- Packaging
- 10mg
- Price
- $1890
- Updated
- 2021/12/16
- Product number
- BB165429
- Product name
- BMS 986205
- Packaging
- 50mg
- Price
- $507.5
- Updated
- 2021/12/16
- Product number
- BB165429
- Product name
- BMS 986205
- Packaging
- 10mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- CS-0021719
- Product name
- Linrodostat
- Purity
- 99.92%
- Packaging
- 5mg
- Price
- $156
- Updated
- 2021/12/16
- Product number
- CS-0021719
- Product name
- Linrodostat
- Purity
- 99.92%
- Packaging
- 10mg
- Price
- $288
- Updated
- 2021/12/16
BMS-986205 Chemical Properties,Usage,Production
Biological Activity
Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.
Description
BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.
Uses
BMS-986205 is a compound being studied for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders.
BMS-986205 Preparation Products And Raw materials
Raw materials
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View Lastest Price from BMS-986205 manufacturers
- Product
- BMS-986205 1923833-60-6
- Price
- US $0.00/gram
- Min. Order
- 1gram
- Purity
- 99%
- Supply Ability
- 10kg
- Release date
- 2022-02-18