ChemicalBook > CAS DataBase List > BMS-986205

BMS-986205

Product Name
BMS-986205
CAS No.
1923833-60-6
Chemical Name
BMS-986205
Synonyms
Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;BMS-986205(Linrodostat);Linrodostat（BMS-986205）;Linrodostat, 10 mM in DMSO;LINRODOSTAT;BMS 986205;BMS986205
CBNumber
CB03339862
Molecular Formula
C24H24ClFN2O
Formula Weight
410.91
MOL File
1923833-60-6.mol
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BMS-986205 Property

Boiling point:
606.8±45.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:42.0(Max Conc. mg/mL);73.75(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);175.59(Max Conc. mM)
form 
Solid
pka
13.80±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B596415
Product name
BMS-986205
Packaging
10mg
Price
$1890
Updated
2021/12/16
Biosynth Carbosynth
Product number
BB165429
Product name
BMS 986205
Packaging
50mg
Price
$507.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
BB165429
Product name
BMS 986205
Packaging
10mg
Price
$145
Updated
2021/12/16
ChemScene
Product number
CS-0021719
Product name
Linrodostat
Purity
99.92%
Packaging
5mg
Price
$156
Updated
2021/12/16
ChemScene
Product number
CS-0021719
Product name
Linrodostat
Purity
99.92%
Packaging
10mg
Price
$288
Updated
2021/12/16
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BMS-986205 Chemical Properties,Usage,Production

Biological Activity

Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.

Description

BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.

Uses

BMS-986205 is a compound being studied for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders.

BMS-986205 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMS-986205 Suppliers

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View Lastest Price from BMS-986205 manufacturers

Zhejiang J&C Biological Technology Co.,Limited
Product
BMS-986205 1923833-60-6
Price
US $0.00/gram
Min. Order
1gram
Purity
99%
Supply Ability
10kg
Release date
2022-02-18

1923833-60-6, BMS-986205Related Search:

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  • BMS-986205
  • Linrodostat
  • LINRODOSTAT;BMS 986205;BMS986205
  • BMS 986205;BMS986205
  • BMS-986205(Linrodostat)
  • CS-2743
  • (2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
  • Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)-
  • (R)-N-(4-Chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
  • Linrodostat（BMS-986205）
  • cis-(αR)-N-(4-Chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methylcyclohexaneacetamide
  • cis-(alphaR)-N-(4-Chlorophenyl)-4-(6-fluoro-quinolin-4-yl)-alpha-methylcyclohexaneacetamide
  • F001287
  • F-001287
  • Linrodostat, 10 mM in DMSO
  • 1923833-60-6
  • 923833-60-6
  • C24H24ClFN2O
  • API