5-BROMO-2-FLUOROANILINE

Product Name: 5-BROMO-2-FLUOROANILINE
CAS No.: 2924-09-6
Chemical Name: 5-BROMO-2-FLUOROANILINE
Synonyms: 0/6/24;5-Bromo Aniline;5-BROMO-2-FLUOROANIL;5-Bromo-2-fuoroaniline;2-Fluoro-5-Bromoaniline;5-BROMO-2-FLUOROANILINE;2,4-di(propan-2-yl)phenol;5-Bromo-2-fluoroaniline ,98%;Benzenamine, 5-bromo-2-fluoro-;1-Amino-5-bromo-2-fluorobenzene
CBNumber: CB0417457
Molecular Formula: C6H5BrFN
Formula Weight: 190.01
MOL File: 2924-09-6.mol

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5-BROMO-2-FLUOROANILINE Property

Melting point:: 27℃
Boiling point:: 105 °C / 12mmHg
Density: 1.694±0.06 g/cm3(Predicted)
refractive index: 1.59
Flash point:: 27 °C
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Solid
pka: 2.13±0.10(Predicted)
color: White or Colorless to Yellow to Orange
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C6H5BrFN/c7-4-1-2-5(8)6(9)3-4/h1-3H,9H2
InChIKey: ADWKOCXRCRSMLQ-UHFFFAOYSA-N
SMILES: C1(N)=CC(Br)=CC=C1F
CAS DataBase Reference: 2924-09-6(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi,Xn
Risk Statements: 22-36-52-36/37/38-20/21/22
Safety Statements: 26-60-36/37-9
RIDADR: 2811
Hazard Note: Toxic
HazardClass: IRRITANT, TOXIC
HazardClass: 6.1
HS Code: 29214990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3043
Product name: 5-Bromo-2-fluoroaniline
Purity: >95.0%(GC)
Packaging: 5g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: B3043
Product name: 5-Bromo-2-fluoroaniline
Purity: >95.0%(GC)
Packaging: 25g
Price: $77
Updated: 2025/07/31

TRC

Product number: B961493
Product name: 5-Bromo-2-fluoroaniline
Packaging: 1g
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-B-05
Product name: 5-Bromo-2-fluoroaniline
Purity: 98%
Packaging: 10g
Price: $10
Updated: 2021/12/16

AK Scientific

Product number: J92178
Product name: 5-Bromo-2-fluoroaniline
Packaging: 5g
Price: $12
Updated: 2021/12/16

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5-BROMO-2-FLUOROANILINE Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

5-Bromo-2-fluoroaniline is used as pharmaceutical intermediate.

Synthesis

364-73-8

2924-09-6

General procedure for the synthesis of 5-bromo-2-fluoroaniline from 4-bromo-1-fluoro-2-nitrobenzene: 5-bromo-2-fluoro nitrobenzene (698 g) was dissolved in 95% ethanol (0.90 L), which was subsequently added to a mixed system of powdered iron (711 g) and saturated aqueous ammonium chloride (2.0 L). The reaction mixture was stirred continuously at 70°C for 24 hours (the reaction process was monitored by HPLC until complete). Upon completion of the reaction, the mixture was cooled to room temperature, filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure to remove the solvent. The residue was subjected to liquid-liquid extraction with ethyl acetate (2 L) and water (2 L) to separate the organic and aqueous phases. The aqueous phase was further extracted once with ethyl acetate (1L). All organic phases were combined, washed with water (1 L), dried with anhydrous magnesium sulfate, filtered and the organic phase was concentrated under reduced pressure. Finally, 545.76 g of 5-bromo-2-fluoroaniline was obtained in 91% yield by high vacuum treatment for 5 h to completely remove the residual ethyl acetate.

References

[1] Patent: WO2006/48761, 2006, A2. Location in patent: Page/Page column 32
[2] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 19, p. 4337 - 4341
[3] Patent: WO2005/94822, 2005, A1. Location in patent: Page/Page column 44
[4] Patent: WO2004/52847, 2004, A2. Location in patent: Page 171
[5] Patent: CN104530107, 2016, B. Location in patent: Paragraph 0022

5-BROMO-2-FLUOROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-FLUOROANILINE Suppliers

Americas 1 China 225 Europe 2 India 5 Japan 1 Sweden 1 United Kingdom 11 United States 22 Global 268

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
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3B Pharmachem (Wuhan) International Co.,Ltd.

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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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View Lastest Price from 5-BROMO-2-FLUOROANILINE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-BROMO-2-FLUOROANILINE 2924-09-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-2-FLUOROANILINE 2924-09-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 5-BROMO-2-FLUOROANILINE 2924-09-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-22

2924-09-6, 5-BROMO-2-FLUOROANILINERelated Search:

3-Fluoro-4-broMoaniline 2-BROMO-3-FLUOROANILINE 3-CHLORO-2,6-DIBROMO-4-FLUOROANILINE 2,4-DIBROMO-6-FLUOROANILINE 5-BROMO-2-FLUOROANILINE 2-(DIFLUOROMETHOXY)BROMOBENZENE 2-(Trifluoromethoxy)bromobenzene 2-Bromo-6-fluoroaniline, 98+%,2-BROMO-6-FLUOROANILINE 2-BROMO-4-FLUOROANILINE,2-Bromo-4-fluoroaniline 99%,2-Bromo-4-fluoroaniline99%,2-BROMO-4-FLUOROANILINE 98+% 4-Bromo-2-fluoroaniline 99%,4-Bromo-2-fluoroaniline99%,-BROMO-2-FLUOROANILINE, 98%,4-Bromo-2-fluoroaniline,98+%,4-BROMO-2-FLUOROANILINE 1-Bromo-3-fluoro-5-nitrobenzene Vandetanib 2,6-Dibromo-4-fluoroaniline 2-Bromo-5-fluoroaniline 98%,2-Bromo-5-fluoroaniline98%,2-BROMO-5-FLUOROANILINE 4-Fluorobenzoyl chloride 3-BROMO-4-FLUOROANILINE,3-Bromo-4-fluoroaniline98%,3-Bromo-4-fluoroaniline 98% 2-Fluoroaniline 5-BROMO-2-FLUOROANILINE HYDROCHLORIDE

5-BROMO-2-FLUOROANILINE

2-Fluoro-5-Bromoaniline

5-Bromo-2-fluoro Aniline 2924-9-6

5-Bromo-2-fluoroaniline ,98%

5-BROMO-2-FLUOROANIL

1-Amino-5-bromo-2-fluorobenzene

5-Bromo-2-fuoroaniline

5-Bromo-2-fluoroaniline≥ 99% (GC)

Benzenamine, 5-bromo-2-fluoro-

5-BROMO-2-FLUOROANILINE ISO 9001：2015 REACH

TIANFU-CHEM CAS:2924-09-6 5-BROMO-2-FLUOROANILINE

2,4-di(propan-2-yl)phenol

5-Bromo Aniline

0/6/24

2924-09-6

29424-09-6

374-25-9

2924-09-4

2924-9-6

2924-09-06

374259

C6H6BrCIFN

Aniline series

Benzenes

Phenol&Thiophenol&Mercaptan

Anilines, Aromatic Amines and Nitro Compounds